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The Role of Platelets in the Early Stages of Atherosclerosis

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Platelets and Atherosclerosis

Abstract

While it is widely accepted that platelets play a significant part in the atherosclerotic process, many view these events as occurring in relation to growth of the plaque, by incorporation of thrombus [1], or the sequelae of thrombus formation on a disrupted plaque, leading to platelet aggregate embolism or occlusive thrombosis [2]. The formation of platelet masses on the surface of disrupted plaques and their dissemination distally causes amaurosis fugax or transient ischemic attacks [3] and is associated with unstable angina and sudden cardiac death [4]. Occlusive thrombus leads to infarction of part of the territory supplied by the occluded artery as in myocardial infarction or gangrene of the foot.

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Authors
  1. S. Moore
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Editors and Affiliations

  1. Klinik für Neurologie der Medizinischen Universität zu Lübeck, Ratzeburger Allee 160, W-2400, Lübeck 1, Germany

    Christof Kessler

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© 1990 Springer-Verlag Berlin Heidelberg

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Moore, S. (1990). The Role of Platelets in the Early Stages of Atherosclerosis. In: Kessler, C. (eds) Platelets and Atherosclerosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58225-7_1

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  • DOI: https://doi.org/10.1007/978-3-642-58225-7_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53006-0

  • Online ISBN: 978-3-642-58225-7

  • eBook Packages: Springer Book Archive

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