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Genes Regulate Effects of Dietary Restriction

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Biological Effects of Dietary Restriction

Part of the book series: ILSI Monographs ((ILSI MONOGRAPHS))

Abstract

Knowledge of how food restriction retards aging processes might suggest clinically useful treatments in man. This nutritional manipulation extends life spans of short-lived rodents, and is most effective if begun early in life (McCay et al. 1939; Ross 1976; Barrows and Kokkonen 1977; Young 1979; Yu et al. 1985; Weindruch et al. 1986). It is the only treatment that consistently extends mammalian life spans beyond the longest known for the species tested without food restriction.

This work was supported by grants AG06232 and AG00594 from the National Institute on Aging and by grant DK25687 from the National Institute on Diabetes and Kidney Disease. These institutes are not responsible for its content, nor do they necessarily represent the official views of those agencies.

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Author information

Authors and Affiliations

  1. The Jackson Laboratory, Bar Harbor, ME, 04609, USA

    D. E. Harrison & J. R. Archer

  2. Mt. Sinai Medical Center, One Gustave Levy Pl, New York, NY, 10029, USA

    B. Kent

Authors
  1. D. E. Harrison
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  2. J. R. Archer
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  3. B. Kent
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Editor information

Editors and Affiliations

  1. 1126 Sixteenth Street, N.W., Washington, DC, 20036, USA

    Lawrence Fishbein PhD

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© 1991 Springer-Verlag Berlin Heidelberg

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Harrison, D.E., Archer, J.R., Kent, B. (1991). Genes Regulate Effects of Dietary Restriction. In: Fishbein, L. (eds) Biological Effects of Dietary Restriction. ILSI Monographs. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58181-6_25

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  • DOI: https://doi.org/10.1007/978-3-642-58181-6_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63494-9

  • Online ISBN: 978-3-642-58181-6

  • eBook Packages: Springer Book Archive

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