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Nichtmedikamentöse Therapie der arteriellen Hypertonie

  • Michael Stimpel

Zusammenfassung

Während der Nutzen einer Blutdrucksenkung im Sinne einer verminderten Morbidität und Mortalität bei allen Schweregraden der Hypertonie nachgewiesen ist, besteht für die Hypertonie vom Schweregrad 1 und niedrigem kardiovaskulärem Gesamtrisiko nach wie vor die Unsicherheit, inwieweit dieser prinzipielle Nutzen einer Blutdrucksenkung durch die Nebenwirkungen einer medikamentösen Therapie aufgehoben wird. Zumindest in zwei größeren, kontrollierten Studien (Hypertension Detection and Follow-up Cooperative Group = HDFP, 1984; Multiple Risk Factor Intervention Trial=MRFIT, 1985) fand sich im Vergleich zu unbehandelten Patienten mit diastolischer Grenzwerthypertonie (90–94 mmHg) eine Zunahme der koronaren Morbidität und Mortalität bei Patienten, die mit antihypertensiv wirksamen Medikamenten behandelt worden waren. Ebenfalls konnte in diesen Studien kein Nutzen einer medikamentösen Intervention nachgewiesen werden bei Patienten mit diastolischen Blutdruckwerten zwischen 95 und 99 mmHg.

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Copyright information

© Steinkopff Verlag Darmstadt 2001

Authors and Affiliations

  • Michael Stimpel
    • 1
  1. 1.Reha Klinik GmbH DampDampGermany

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