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Die molekulare Kardiologie bei Frauen

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Die koronare Herzkrankheit der Frau

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Zusammenfassung

Geschlechtsspezifische Unterschiede bei kardiovaskulären Erkrankungen sind empirisch bekannt, ihre molekularen Grundlagen werden jedoch erst in jüngster Zeit systematisch untersucht. Dazu gehören einmal östrogen-abhängige Mechanismen, die Funktionsvarianten auf zellulärer Ebene induzieren. Östrogene beeinflussen die Expression und Funktion zahlreicher Gene und Proteine im kardiovaskulären System. Unter anderem führen Östrogene zu einer vermehrten Verfügbarkeit von Stickoxid (NO), zu Vasodilatation und Vasoprotektion.

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Authors
  1. V. Regitz-Zagrosek
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  2. R. Hetzer
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Editor information

Editors and Affiliations

  1. Klinikum Coburg II. Med. Klinik — Kardiologie, Ketschendorfer Str. 33, 96450, Coburg, Deutschland

    Johannes Brachmann  & Hans Jochen Medau  & 

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© 2002 Springer-Verlag Berlin Heidelberg

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Regitz-Zagrosek, V., Hetzer, R. (2002). Die molekulare Kardiologie bei Frauen. In: Brachmann, J., Medau, H.J. (eds) Die koronare Herzkrankheit der Frau. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57534-1_19

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  • DOI: https://doi.org/10.1007/978-3-642-57534-1_19

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-642-63290-7

  • Online ISBN: 978-3-642-57534-1

  • eBook Packages: Springer Book Archive

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