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Stroke MRI pp 23-29 | Cite as

Perfusion-weighted MM (PWI)

  • P. D. Schellinger
  • J. B. Fiebach
  • S. Heiland
  • K. Sartor
Chapter
  • 211 Downloads

Abstract

The term perfusion normally refers to the delivery of blood at the capillary level, where the metabolic exchange of nutrients and oxygen takes place. Perfusion-weighted MR imaging (PWI) allows the measurement of capillary perfusion with the dynamic susceptibility contrast-enhanced (DSC) technique. A paramagnetic contrast agent is injected as an intravenous bolus and the signal change is tracked by ultrafast MR sequences in the area of interest [283, 284, 358]. Analogous to concentration time curves obtained with, e.g., Swan Ganz (pulmonary artery) catheters after injection of ice water (temperature probe) or indocyanine green (infrared probe), cerebrovascular (as opposed to cardiac output or vascular resistance measurements) hemodynamic parameters can be derived from the MR-de-rived contrast-bolus over time curve.

Keywords

Contrast Agent Cerebral Blood Flow Cerebral Blood Volume Infarct Core Contrast Bolus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • P. D. Schellinger
  • J. B. Fiebach
  • S. Heiland
  • K. Sartor

There are no affiliations available

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