The most widely available tool to non-inva-sively assess extracranial and intracranial vessel status is Doppler/duplex ultrasound  which is a suitable bedside tool not only for baseline vessel status but also to monitor the process or absence of recanalization, whether rt-PA is applied or not. Already early DU-re-ports described that rapid recanalization is associated with a higher rate of clinical improvement and smaller infarcts at outcome . Clinical recovery from stroke correlates with the timing of arterial recanalization after thrombolysis, complete recanalization was common in patients who had follow-up Rankin Scores of 0 to 1 (P = 0.006) . rt-PA results in a faster recanalization, significantly higher recanalization rate (66% versus 15% in controls), and therefore in a significantly smaller infarct volume and a significantly better clinical outcome at 3 months [5, 227]. Secondary ICH, which is associated with a worse clinical outcome, is significantly more frequent in patients with late rather than early recanalization .
KeywordsCerebral Blood Flow Acute Stroke Acute Ischemic Stroke Cerebral Blood Volume Acute Stroke Patient
Unable to display preview. Download preview PDF.