Zusammenfassung
Die Prävalenz der fortgeschrittenen Herzinsuffizienz beträgt in den westlichen Industrieländern ca. 0,1%. In Deutschland sind davon ungefähr 80000 Menschen betroffen (3). Die Einführung neuer medikamentöser Therapien hat zwar wesentliche Verbesserungen in der Behandlung der Herzinsuffizienz gebracht. Trotzdem bleibt für viele Patienten mit schwerer Herzinsuffizienz eine Herztransplantation die einzige Therapieoption. Aufgrund des Mangels an Spenderorganen können jedoch nicht alle Patienten, die davon einen Überlebensvorteil erfahren würden, mit dieser Therapie behandelt werdenr. Ein Drittel dieser Patienten verstirbt auf der Warteliste zur Herztransplantation (4). Um solche Patienten bis zur Verfügbarkeit eines geeigneten Spenderorgans am Leben erhal-ten zu können, wurden mechanische Kreislaufunterstutzungssysteme entwickelt. Zu diesen gehörte als eines der ersten Systeme, das klinische Anwendung fand, das HeartMate I.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Ankersmit HJ, Edwards NM, Schuster M, John R, Kocher A, Rose EA, Oz M, Itescu S (1999) Quantitative changes in T-cell populations after left ventricular assist device implantation: relationship to T-cell apoptosis and soluble CD95. Circulation 100 (Suppl): II211–II215
Bonkohara Y, Minami K, Arusoglu L, El-Banayosy A, Fey O, Sarnowski P, Körfer R (1999) A fatal mechanical disorder of the TCI HeartMate left ventricular assist system. J Thorac Cardiovasc Surg 118: 769–770
Deng MC, Breithardt G, Scheld HH (1999) Towards an evidence based perspective in advanced heart failure care. Z Kardiol 88 (Suppl 3): III/1-III/4
Deng MC, De Meester JM, Smits JM, Heinecke J, Scheld HH (2000) Effect of receiving a heart transplant: analysis of a national cohort entered on to a waiting list, stratified by heart failure severity. Comparative Outcome and Clinical Profiles in Transplantation (COCPIT) Study Group. BMJ 321 (7260): 540–545
DeRose JJ Jr, Umana JP, Argenziano M, Catanese KA, Gardocki MT, Flannery M, Levin HR, Sun BC, Rose EA, Oz MC (1997) Implantable left ventricular assist devices provide an excellent outpatient bridge to transplantation and recovery. J Am Coll Cardiol 30: 1773–1777
El-Amir NG, Gardocki M, Levin HR, Markowitz DD, Greenspan RL, Catanese KA, Rose EA, Oz MC (1996) Gastrointestinal consequences of left ventricular assist device placement. ASAIO J 42: 150–153
El-Banayosy A, Arusoglu L, Kizner L, Tenderich G, Minami K, Inoue K, Körfer R (2000) Novacor left ventricular assist system versus TCI HeartMate vented electric left ventricular assist system as a long-term mechanical circulatory support device in bridging patients: a prospective study. J Thorac Cardiovasc Surg 119: 581–587
Frazier OH, Rose EA, Oz MC, Dembitsky W, McCarthy P, Radovancevic B, Poirier VL, Dasse KA (2001) Multicenter clinical evaluation of the HeartMate I vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg 122: 1186–1195
Graham TR, Dasse K, Coumbe A, Salih V, Marrinan MT, Frazier OH, Lewis CT (1990) Neointimal development on textured biomaterial surfaces during clinical use of an implantable left ventricular assist device. Eur J Cardiothorac Surg 4: 182–190
HeartMate VE Operating Manual (1995) TCI Thermo Cardiosystems, Inc., Woburn, Massachusetts, USA
Maher TR, Butler KC, Poirier VL, Gernes DB (2001) TCI HeartMate left ventricular assist devices: a multigeneration of implanted blood pumps. Artif Organs 25: 422–426
Mancini DM, Beniaminovitz A, Levin H, Catanese K, Flannery M, DiTullio M, Savin S, Cordisco ME, Rose E, Oz M (1998) Low incidence of myocardial recovery after left ventricular assist device implantation in patients with chronic heart failure. Circulation 98: 2383–2389
Oz MC, Argenziano M, Catanese KA, Gardocki MT, Goldstein DJ, Ashton RC, Gelijns AC, Rose EA, Levin HR (1997) Bridge experience with long-term implantable left ventricular assist devices. Are they an alternative to transplantation? Circulation 95: 1844–1852
Oz MC, Rose EA, Levin HR (1995) Selection criteria for placement of left ventricular assist devices. Am Heart J 129: 173–177
Peterze B, Lonn U, Jansson K, Rutberg H, Casimir-Ahn H, Nylander E (2002) Long-term follow-up of patients treated with an implantable left ventricular assist device as an extended bridge to heart transplantation. J Heart Lung Transplant 21: 604–607
Piccione W Jr (2000) Left ventricular assist device implantation: short and long-term surgical complications. J Heart Lung Transplant 19 (Suppl): S89–S94
Piccione W, Kao WG, Mattea A, Rodriguez ER, Trohman RG (1998) Failure of an implantable left ventricular assist device: a distinctive electrocardiographic pattern before malfunction. J Thorac Cardiovasc Surg 115: 1376–1378
Robbins RC, Kown MH, Portner PM, Oyer PE (2001) The totally implantable Novacor left ventricular assist system. Ann Thorac Surg 71(Suppl): S162–S165
Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, Long JW, Ascheim DD, Tierney AR, Levitan RG, Watson JT, Meier P, Ronan NS, Shapiro PA, Lazar RM, Miller LW, Gupta L, Frazier OH, Desvigne-Nickens P, Oz MC, Poirier VL (2001) Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group. Long-term mechanical left ventricular assistance for end-stage heart failure. N Engl J Med 345: 1435–1443
Scheid HH, Hammel D, Schmid C, Weyand M, Deng M, Mollhoff T, Kerber S (1996) Beating heart implantation of a wearable NOVACOR left-ventricular assist device. Thorac Cardiovasc Surg 44: 62–66
Scheid HH, Soeparwata R, Schmid C, Loick M, Weyand M, Hammel D (1997) Rupture of inflow conduits in the TCI-HeartMate I system. J Thorac Cardiovasc Surg 114: 287–289
Schmid C, Scheid HH, Hammel D (2000) Control of perigraft bleeding during ventricular assist device implantation. Ann Thorac Surg 69: 958–959
Stevenson LW, Kormos RL (2001) Mechanical cardiac support 2000: Current applications and future trial design. J Heart Lung Transplant 20:1–238
Wasler A, Springer WE, Radovancevic B, Myers TJ, Stutts LA, Frazier OH (1996) A comparison between intraperitoneal and extraperitoneal left ventricular assist system placement. ASAIO J 42: M573–M576
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Wilhelm, M.J., Rötger, J. (2003). TCI-HeartMate I (IP/VE). In: Feindt, P., Vetter, H.O., Weyand, M. (eds) Synopsis der biologischen und mechanischen Kreislaufunterstützung. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57385-9_11
Download citation
DOI: https://doi.org/10.1007/978-3-642-57385-9_11
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-642-63252-5
Online ISBN: 978-3-642-57385-9
eBook Packages: Springer Book Archive