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Transkranielle Magnetstimulation in der neuropsychiatrischen Forschung

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Book cover Elektromagnetische Therapien in der Psychiatrie

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Zusammenfassung

Die Anwendung der transkraniellen Magnetstimulation (TMS) in der neuropsychiatrischen Forschung hat in den letzten Jahren erheblich an Bedeutung gewonnen. Mit der TMS bietet sich Wissenschaftlern erstmals die Möglichkeit, das Gehirn gesunder, wacher Erwachsener nichtinvasiv und gezielt zu stimulieren. Auf diese Weise kann einerseits die Erregbarkeit einzelner Areale bestimmt, andererseits aber auch deren Aktivität moduliert werden. Veränderungen kortikaler Erregbarkeit aufgrund von pharmakologischen Interventionen und physiologischen bzw. pathologischen Prozessen können dementsprechend ebenso untersucht werden wie die Lokalisation bestimmter Funktionen. Die dabei gewonnenen Erkenntnisse können zur Erweiterung des Verständnisses von Topographie und funktioneller Architektur kortikaler Physiologie, adaptiver und maladaptiver plastischer Veränderungen, sowie der Pathophysiologie von strukturellen und funktionellen Störungen des zentralen Nervensystems dienen. Die gezielte und kontrollierte Modulation kortikaler Erregbarkeit (Exzitabilität) durch repetitive TMS bietet darüber hinaus neue therapeutische Ansatzpunkte.

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  1. Universitätsklinik für Psychiatrie und Psychotherapie, Osianderstraße 24, 72076, Tübingen, Germany

    C. Plewnia

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    Gerhard W. Eschweiler , Barbara Wild  & Mathias Bartels ,  & 

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Plewnia, C. (2003). Transkranielle Magnetstimulation in der neuropsychiatrischen Forschung. In: Eschweiler, G.W., Wild, B., Bartels, M. (eds) Elektromagnetische Therapien in der Psychiatrie. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57370-5_19

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