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Diagnosis and Treatment of Infection

  • Chapter
Surgery

Abstract

Over the span of recorded history, the occurrence of serious infection after injury has been the rule rather than the exception, such sequelae of our interaction with the microbial world often resulting in death. For centuries, infection after traumatic wounding was considered a desirable outcome, as evidenced by the epithet “laudable pus,33” which, once drained, was associated with wound healing in those patients who were able to survive both the inciting event and the ensuing infection. During the last century, the development and use of anesthesia, fluid resuscitation, blood transfusion, and hemodynamic monitoring were key advances that allowed surgical practitioners to carry out increasingly complex procedures. However, before the widespread application of aseptic surgical technique and the subsequent discovery and therapeutic use of antimicrobial agents, the evolution and performance of even routine surgical procedures was hindered by the frequent association with serious, often life-threatening infections.

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Authors
  1. David L. Dunn
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Editors and Affiliations

  1. University of California, San Francisco, USA

    Jeffrey A. Norton MD (Professor and Vice-Chairman of Surgery, Chief) (Professor and Vice-Chairman of Surgery, Chief)

  2. Surgical Service, San Francisco VA Medical Center, San Francisco, California, USA

    Jeffrey A. Norton MD (Professor and Vice-Chairman of Surgery, Chief) (Professor and Vice-Chairman of Surgery, Chief)

  3. Division of General Surgery, Duke University Medical Center, Durham, North Carolina, USA

    R. Randal Bollinger MD, PhD (Professor of Surgery, Professor of Immunology, Chief) (Professor of Surgery, Professor of Immunology, Chief)

  4. Division of Surgical Oncology, University of Michigan, Comprehensive Cancer Center, Ann Arbor, Michigan, USA

    Alfred E. Chang MD (Chief, Hugh Cabot Professor of Surgery) (Chief, Hugh Cabot Professor of Surgery)

  5. Department of Surgery, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA

    Stephen F. Lowry MD (Professor and Chairman) (Professor and Chairman)

  6. Division of General Surgery, University of California, San Francisco, San Francisco, California, USA

    Sean J. Mulvihill MD (Professor of Surgery, Chief) (Professor of Surgery, Chief)

  7. Karmanos Cancer Institute, Wayne State University, Harper Hospital, Detroit, Michigan, USA

    Harvey I. Pass MD (Professor of Surgery and Oncology, Chief of Thoracic Oncology) (Professor of Surgery and Oncology, Chief of Thoracic Oncology)

  8. Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, USA

    Robert W. Thompson MD (Associate Professor of Surgery) (Associate Professor of Surgery)

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Dunn, D.L. (2001). Diagnosis and Treatment of Infection. In: Norton, J.A., et al. Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57282-1_11

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