Virus Detection in Biopsy Specimens

  • Veijo Hukkanen
  • Pirkko Heino
Part of the Springer Lab Manuals book series (SLM)


We describe nonradioactive in situ hybridization (ISH) approaches for localization of viral DNA and RNA sequences in infected tissue. The use of non-isotopic ISH methods has become common because they are now as sensitive as autoradiography but they do not have the the disadvantages of the isotopic methods, such as the long assay time and the requirement for special laboratory facilities (Musiani et al., 1994).


Human Papilloma Virus Trigeminal Ganglion Acetic Anhydride Virus Detection Concentration Of200 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • Veijo Hukkanen
    • 1
  • Pirkko Heino
    • 2
  1. 1.University ofTurkuDepartment ofVirologyTurkuFinland
  2. 2.University ofWisconsin Medical SchoolMcArdle Laboratory for Cancer Research, 1400 University Ave., MadisonUSA

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