PRINS: PrimedIn SituLabeling and Hybridization in One Step
PRINS (PRimed IN Situ labeling and hybridization in one step) is a technique superbly suited for the detection of tandemly repeated target sequences in chromosomes and nuclei (in situ) by oligonucleotide probes. Such sequences can be detected down to a target size of a few hundred bases with a simple short procedure rendering virtually 100% of potential targets labeled.
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