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Chlamydia pneumoniae, APOE genotype, and Alzheimer’s disease

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Chlamydia pneumoniae and Chronic Diseases

Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative condition associated with atrophy and death of nerve cells in affected brain regions. This disease is relatively common, affecting 4 million or more individuals in the United States alone [1]. AD occurs in two relatively distinct forms: an early-onset, familial form and a more common late-onset, sporadic form. Incidence of the latter increases with increasing age, and AD is considered to be the most significant single cause of senile dementia. Indeed, a number of studies have indicated that at least half the total number of cases of dementia in the elderly are attributable to AD [2].

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Authors
  1. A. P. Hudson
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  2. H. C. Gérard
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  3. J. A. Whittum-Hudson
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  4. D. M. Appelt
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  5. B. J. Balin
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Editor information

Editors and Affiliations

  1. Robert Koch-Institut, Nordufer 20, D-13353, Berlin, Germany

    Johanna L’age-Stehr

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© 2000 Springer-Verlag Berlin Heidelberg

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Hudson, A.P., Gérard, H.C., Whittum-Hudson, J.A., Appelt, D.M., Balin, B.J. (2000). Chlamydia pneumoniae, APOE genotype, and Alzheimer’s disease. In: L’age-Stehr, J. (eds) Chlamydia pneumoniae and Chronic Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57195-4_19

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  • DOI: https://doi.org/10.1007/978-3-642-57195-4_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41136-9

  • Online ISBN: 978-3-642-57195-4

  • eBook Packages: Springer Book Archive

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