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Medical Therapy of Portal Hypertension

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Portal Hypertension

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Portal hypertension (PH) is a syndrome defined by a pathological increase in the portal venous pressure above its physiological values or an increase in the hepatic venous pressure gradient (HVPG) above 3–5 mmHg. When the HVPG rise above the threshold of 10–12 mmHg, complications of PH may occur; therefore this cut-off defines patients with clinically significant PH (GARCIA-TsAO et al. 1985). Complications of PH are identified in: gastrointestinal bleeding from ruptured gastro-esophageal varices or portal hypertensive gastropathy, ascites and metabolic disorders. According to the anatomicallocation of the obstruction to the blood flow, we distinguish prehepatic, intrahepatic and posthepatic PH.

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Authors and Affiliations

  1. Department of Clinical Medicine, Division of Gastroenterology, Piazzale delle Province n 11, 00162, Rome, Italy

    R. Lionetti MD

  2. Professor, Department of Clinical Medicine, Division of Gastroenterology, Viale dell’Università n 37, 00185, Rome, Italy

    L. Capocaccia MD & A. Masini MD

  3. Department of Clinical Medicine, Division of Gastroenterology, Viale dell’Università n 37, 00185, Rome, Italy

    C. Efrati MD

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  1. Department of Radiology, University of Rome “La Sapienza” Policlinico Umberto I, Viale Regina Elena n. 324, I-00161, Rome, Italy

    P. Rossi (Professor and Chairman), P. Ricci  & L. Broglia (Professor and Chairman),  & 

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Capocaccia, L., Lionetti, R., Efrati, C., Masini, A. (2000). Medical Therapy of Portal Hypertension. In: Rossi, P., Ricci, P., Broglia, L. (eds) Portal Hypertension. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57116-9_13

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