Skip to main content

Pathophysiologie des Ösophagus

  • Chapter
Pathophysiologie

Part of the book series: Springer Lehrbuch ((SLB))

  • 427 Accesses

Zusammenfassung

Ein 35 jähriger Mann klagt seit 3 Jahren über anfallsartige retrosternale Schmerzen, die häufig postprandial beginnen. Wiederholte kardiologische Diagnostik, einschließlich der Koronarangiographie hatten keine Hinweise für das Vorliegen einer koronaren Herzkrankheit ergeben. Schließlich wurde der Patient, bei dem bereits eine Herzneurose vermutet wurde, einer gastroenterologischen Diagnostik zugeführt. Die Gastroskopie blieb unauffällig, bei der Manometrie jedoch fanden sich Motilitätsstörungen im Sinne von simultanen Kontraktionen in 50% der Naß- und Trockenschluckakte bei normalem UÖS.Im Ösophagusbreischluck zeigte sich das Bild eines Korkenzieherösophagus. Die Befunde sind typisch für die Diagnose eines diffusen Ösophagusspasmus.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Aggestrup S et al. (1985) Lack of vasoactive intestinal polypeptide nerves in achalasia. Gastroenterology 84: 924–927

    Google Scholar 

  2. Clouse RE, Diamant NE (1998) Motor physiology and motor disorders of the esophagus. In: Sleisinger MH and Fordtran JS (eds) Gastrointestinal and Liver Disease (6th ed). WB Saunders, Philadelphia London Toronto Montreal Sydney Tokio, pp 467–497

    Google Scholar 

  3. Galmiche JP, Janssens J (1995) The pathophysiology of gastroesophageal reflux disease: an overview. Scand J Gastroenterol 30 (Suppl211): 7–18

    Article  Google Scholar 

  4. Kahrilas [P] (1996) Esophageal motility disorders: Pathogenesis, diagnosis, treatment. In: Champion MC, Orr WC (eds) Evolving concepts in gastrointestinal motility. Blackwell Science, Oxford, pp 15–45

    Google Scholar 

  5. Kahrilas PJ et al. (1988) The effect of peristaltic dysfunction on esophageal volume clearance. Gastroenterology 94: 73–80

    PubMed  CAS  Google Scholar 

  6. Katz PO et al. (1986) Abnormal esophageal pressures in reflux esophagitis: cause or effect? Am J Gastroenterol 81: 744–746

    PubMed  CAS  Google Scholar 

  7. Katzka DA et al. (1995) Hypertensive lower esophageal sphincter pressures and gastroesophageal reflux: an apparent paradox that is not unusual. Am J Gastroenterol 90: 280–284

    PubMed  CAS  Google Scholar 

  8. Koelz HR (1990) Pathophysiologic des Oesophagus. In: Sie-wert JR, Harder F, Allgöwer M, Blum AL, Creutzfeldt W, Hollender LF, Peiper HJ (Hrsg) Chirurgische Gastroenterologie (2. Aufl). Springer, Berlin Heidelberg New York, pp 467–478

    Google Scholar 

  9. Mearin et al. (1993) Patients with achalasia lack nitric oxide synthase in the gastroesophageal junction. Eur J Clin Invest 23: 724–728

    Article  PubMed  CAS  Google Scholar 

  10. Mittal RK et al. (1995) Transient lower esophageal sphincter relaxation. Gastroenterology 109: 601–610

    Article  PubMed  CAS  Google Scholar 

  11. Mittal RK, Balaban DH (1997) The esophagogastric junction. N Engl J Med 336: 924–932

    Article  PubMed  CAS  Google Scholar 

  12. Mittal RK et al. (1996) Characteristics of lower esophageal sphincter relaxation induced by pharyngeal stimulation with minute amounts of water. Gastroenterology 111: 378–384

    Article  PubMed  CAS  Google Scholar 

  13. Richter JE (1995) Motility disorders of the esophagus. In: Yamada T, Alpers DH, Owyang C, Powell DW, Silverstein FE (eds) Textbook of Gastroenterology (2nd ed). JB Lippincott, Philadelphia, pp 1174–1213

    Google Scholar 

  14. Sarosiek J et al. (1996) Enhancement of salivary esophagopro-tection: Rationale for a physiological approach to gastroesophageal reflux disease. Gastroenterology 110: 675–681

    Article  PubMed  CAS  Google Scholar 

  15. Sontag SJ et al. (1991) The importance of hiatal hernia in reflux esophagitis compared with lower esophageal sphincter pressure or smoking. J Clin Gastroenterol 13: 628–643

    Article  PubMed  CAS  Google Scholar 

  16. Vaezi MF, Richter JE (1996) Role of acid and duodenogas-troesophageal reflux in gastroesophageal reflux disease. Gastroenterology 111: 1192–1199

    Article  PubMed  CAS  Google Scholar 

  17. Vaezi MF, et al. (1995) Role of acid and duodenogastric reflux in esophageal injury: a review of animal and human studies. Gastroenterology 108: 1897–1907

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Katsoulis, S. (2000). Pathophysiologie des Ösophagus. In: Pathophysiologie. Springer Lehrbuch. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57115-2_17

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-57115-2_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63004-0

  • Online ISBN: 978-3-642-57115-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics