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Incidence of Apoptosis and Its Pathological and Biochemical Manifestations

  • Chapter
Apoptosis and Its Modulation by Drugs

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 142))

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Abstract

This volume is dedicated to the study of apoptosis and its modulation by drugs. The purpose of the book is to present (a) the molecular mechanisms of cell death by apoptosis in a comprehensive and stimulating manner, (b) the potential critical role of apoptosis in modifying selected diseases, and (c) a review of the effect of various drugs and chemicals on apoptosis. Studying apoptosis is a “hot” topic in research at present and it is applicable to many different areas of scientific and medical investigations. Contributors to this book are leading experts in this field, and the various papers attempt to synthesize views on basic mechanisms and molecular and genetic regulations. Several chapters present morphological changes through specific mediators, activators, and inhibitors, leading to final clinical end points of various diseases and to important diagnostic indicators of these conditions.

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  1. R. Cameron
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  2. G. Feuer
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  1. Department of Pathology Toronto Hospital, General Division, University of Toronto, 200 Elizabeth Street, Toronto, Ontario, Canada, M5G 2C4

    Ross G. Cameron M.D., Ph.D.

  2. Banting Institute Department of Clinical Biochemistry, University of Toronto, Toronto, Ontario, Canada, M5G 2C4

    George Feuer Ph.D., C. Med. Sci.

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Cameron, R., Feuer, G. (2000). Incidence of Apoptosis and Its Pathological and Biochemical Manifestations. In: Cameron, R.G., Feuer, G. (eds) Apoptosis and Its Modulation by Drugs. Handbook of Experimental Pharmacology, vol 142. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57075-9_1

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