Abstract
Laser induced fluorescence spectra were obtained from atherosclerotic plaque samples, in order to discriminate areas in the plaque of different composition. Different excitation wavelengths were used: 488nm and 476nm, provided by a c.w. Ar+ laser, 457.9nm, provided by a c.w. Kr+ laser, and 337.1nm, provided by a pulsed N2 laser. All samples were histopathologically examined and showed three areas of different composition: fibrous tissue, lipid constituents and calcified plaque. Spectra corresponding to these areas were analyzed and mathematical fittings were performed, in order to reproduce each spectrum as a correlation of multiple Gaussian peaks. An effort was made to discriminate the composition of the plaque from the information obtained by the corresponding spectra.
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© 2000 Springer-Verlag Berlin Heidelberg
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Makropoulou, M. et al. (2000). Laser Induced Fluorescence in Atherosclerotic Plaque with Different Excitation Wavelengths. In: Fotakis, C., Papazoglou, T.G., Kalpouzos, C. (eds) Optics and Lasers in Biomedicine and Culture. Series of the International Society on Optics Within Life Sciences, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56965-4_64
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DOI: https://doi.org/10.1007/978-3-642-56965-4_64
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