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Purinergic and Pyrimidinergic Signalling II pp 3–32Cite as

P1 Receptors in the Cardiovascular System

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 151 / 2))

Abstract

The presence of adenosine receptors on cardiovascular tissues has previously been established on the basis of functional responses to adenosine and adenosine analogs. Specific functions attributed to each of the four adenosine receptor subtypes (A1, A2A, A2B, and A3) are discussed in detail below following a summary of the direct evidence for adenosine receptors in cardiovascular tissues based on the detection of receptor transcripts or protein.

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  1. Health Sciences Center, University of Virginia, Box 801395, Charlottesville, VA, 22908, USA

    R.M. Broad & Joel Linden

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  1. Institute of Pharmacological Sciences, University of Milan, Via Balzaretti, 9, 20133, Milan, Italy

    Maria Pia Abbracchio

  2. Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Searle 8-477 (S-215) 303 East Chicago Avenue, Chicago, IL, 60611

    Michael Williams

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Broad, R., Linden, J. (2001). P1 Receptors in the Cardiovascular System. In: Abbracchio, M.P., Williams, M. (eds) Purinergic and Pyrimidinergic Signalling II. Handbook of Experimental Pharmacology, vol 151 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56921-0_1

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