Skip to main content

Leberzirrhose und portale Hypertension

  • Chapter
Therapie von Leber- und Gallekrankheiten
  • 78 Accesses

Zusammenfassung

Das gemeinsame Endstadium der meisten chronischen Leberkrankheiten ist die Leberzirrhose. Eine medikamentöse Therapie der Zirrhose selbst gibt es nicht, behandeln lassen sich nur ihre Komplikationen, wie Pfortaderhochdruck, Aszites und hepatische Enzephalopathie. Neben der endoskopischen und medikamentösen Therapie steht die operative Behandlung.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Angelico M, Carli L, Piat C, et al., (1993) Isosorbide-5-mononitrate versus propranolol in the prevention of first bleeding in cirrhosis. Gastroenterology 104:1460–1465

    PubMed  CAS  Google Scholar 

  • Besson I, Ingrand P, Person B, et al., (1995) Sclerotherapy with or without octreotide for acute variceal bleeding. N Engl J Med 333:555–560

    Article  PubMed  CAS  Google Scholar 

  • Brocchi E, Caletti G, Brambilla G, et al., (1988) Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study. N Engl J Med 319:983–989

    Article  Google Scholar 

  • Conn HO, Rambsby GR, Storer EH, et al., (1975) Intraarterial vasopressin in the treatment of upper gastrointestinal hemorrhage: a prospective controlled clinical trial. Gastroenterology 68:211–221

    PubMed  CAS  Google Scholar 

  • D’Amico G, Pagliaro L, Bosch J (1995) The treatment of portal hypertension: a meta-analytic review. Hepatology 22:332–354

    Article  CAS  Google Scholar 

  • Feretis C, Dimopoulos C, Benakis P, et al., (1995) N-Butyl-2-cyanoacrylate (Histoacryl) plus sclerotherapy versus sclerotherapy alone in the treatment of bleeding esophageal varices: a randomized prospective study. Endoscopy 27:355–357

    Article  PubMed  CAS  Google Scholar 

  • Grace ND (1992) Prevention of initial variceal hemorrhage. Gastroenterol Clin North Am 21:149–161

    PubMed  CAS  Google Scholar 

  • Hashizume M, Kitano S, Koyanagi N, et al., (1992) Endoscopic injection sclerotherapy for 1000 patients with esophageal varices: A nine-year prospective study. Hepatology 15:69–75

    Article  PubMed  CAS  Google Scholar 

  • Jutabha R, Jensen DM, See J, et al., (1995) Randomized, controlled study of various agents for endoscopic injection sclerotherapy of bleeding canine gastric varices. Gastrointest Endosc 41:206–211

    Article  PubMed  CAS  Google Scholar 

  • Kitano S, Terblanche J, Kahn D, et al., (1986) Venous anatomy of the lower oesophagus in portal hypertension: practical implication. Br J Surg 73:525–531

    Article  PubMed  CAS  Google Scholar 

  • Kleber G, Sauerbruch T, Ansari H, et al., (1991) Prediction of variceal hemorrhage in cirrhosis: A prospective follow-up study. Gastroenterology 100:1332–1337

    PubMed  CAS  Google Scholar 

  • Lebrec D, Poynard T, Hillon P, et al., (1981) Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis. N Engl J Med 305:1371–1374

    Article  PubMed  CAS  Google Scholar 

  • Orlof MJ, Orloff MS, Orloff SL, et al., (1995) Treatment of bleeding from portal hypertensive gastropathy by portocaval shunt. Hepatology 21:1011–1017

    Google Scholar 

  • Papatheodoridis GV, Goulis J, Leandro G, et al., (1999) Transjugular intrahepatic portosystemic shunt compared with endoscopie treatment for prevention of variceal rebleeding: a meta-analysis. Hepatology 30:612–622

    Article  PubMed  CAS  Google Scholar 

  • Rigo GP, Merighi A, Chahin NJ, et al., (1992) A prospective study of the ability of three endoscopie classifications to predict hemorrhage from esophageal varices. Gastrointest Endosc 38:425–429

    Article  PubMed  CAS  Google Scholar 

  • Sarin SK, Lamba GS, Kumar S, et al., (1999) Comparison of endoscopie ligation and propranolol for the primary prevention of variceal bleeding. N Engl Med 340:988–993

    Article  CAS  Google Scholar 

  • Sato T, Yamazaki K, Toyota J, et al., (1999) Evaluation of magnetic resonance angiography in detection of gastric varices. J Gastroenterol 34:321–326

    Article  PubMed  CAS  Google Scholar 

  • Seifert H, Schmitt T, Gültekin T, Caspary WF, Wehrmann T (2000) Synergistic sedation with propofol plus midazolam vs. sedation with propofol alone for interventional endoscopie procedures: a randomized prospective study. Aliment Pharmacol Ther (im Druck)

    Google Scholar 

  • Silverstein FE, Tytgat GNJ (Hrsg) (1994) Gastroenterologische Endoskopie. Thieme, Stuttgart

    Google Scholar 

  • Soehendra N, Nam VC, Grimm H, Kempeneers I (1986) Endoscopie obliteration of large esophageal varices with bycrylate. Endoscopy 18:25–26

    Article  PubMed  CAS  Google Scholar 

  • Spina GP, Arcidiacono R, Bosch J, et al., (1994) Gastric endoscopic features in portal hypertension: final report of a consensus conference, Milan, Italy, September 19, 1992. J Hepatol, 21:461–467

    Article  PubMed  CAS  Google Scholar 

  • Stiegmann GV, Goff JS, Michaletz-Onody PA, et al., (1992) Endoscopic sclerotherapy as compared with endoscopie ligation for bleeding esophageal varices. N Engl J Med 326:1527–1532

    Article  PubMed  CAS  Google Scholar 

  • Svoboda P, Kantorova I, Ochmann J, Kozumplik L, Marsova J (1999) A prospective randomized controlled trial of sclerotherapy vs ligation in the prophylactic treatment of high-risk esophageal varices. Surg Endoscopy 13:580–584

    Article  CAS  Google Scholar 

  • Thakeb F, Salama Z, Raouf TA, et al., (1995) The value of combined use of N-butyl-2-cyanoacrylate and ethanolamine oleate in the management of bleeding oesophagogastric varices. Endoscopy 27:358–364

    Article  PubMed  CAS  Google Scholar 

  • The North Italian Endoscopie Club for the Study and Treatment of Esophageal Varices (1988): Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A protective multicenter study. N Engl J Med 319:983–989

    Article  Google Scholar 

  • Vianna A, Hayes PC, Moscoso G, et al., (1987) Normal venous circulation of the gastroesophageal junction: A route to understanding varices. Gastroenterology 93:876–889

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Seifert, H., Leuschner, U. (2001). Leberzirrhose und portale Hypertension. In: Caspary, W.F., Leuschner, U., Zeuzem, S. (eds) Therapie von Leber- und Gallekrankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56819-0_28

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-56819-0_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63151-1

  • Online ISBN: 978-3-642-56819-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics