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Die Alteration des Stress- und Immunsystems bei laparoskopischen Operationen wird entscheidend von der Art des Eingriffes beeinflusst

Alteration in the stress and immune system after laparoscopic procedures depends on the type of operation

  • Conference paper
Chirurgisches Forum 2001 für experimentelle und klinische Forschung

Part of the book series: Deutsche Gesellschaft für Chirurgie ((FORUMBAND,volume 30))

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Abstract

We present two experiments to compare laparoscopic to conventional oncological surgery regarding short-term aspects (stress and immune alteration). Material and Methods: We established two syngenec tumor bearing small animal models for colon resection (BSp73 ASML, BDX rats) and liver resection (Morris hepatoma 3924A, ACI rats). The following parameters of the stress and immune system were measured: corticosterone, neopterine, IL-1ß, IL-6 and the body weight as a parameter of postoperative recovery. Results: After colon resection the analysis of variance (ANOVA) showed significant differences in all short-term parameters, including body weight after laparoscopic versus conventional colon resection (p < 0.05). In the case of liver resection only IL-6 showed significant differences (p < 0.05). Conclusion: These results suggest that the type of intraabdominal operation (colon or liver) may influence the trauma of an operation more than the type of technique (laparoscopic or open).

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Authors and Affiliations

  1. Chirurgische Universitätsklinik Heidelberg, Germany

    Dr. Chr. Kuntz, P. Schwalbach, M. Schmeding & Ch. Herfarth

Authors
  1. Dr. Chr. Kuntz
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  2. P. Schwalbach
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  3. M. Schmeding
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  4. Ch. Herfarth
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Corresponding author

Correspondence to Chr. Kuntz .

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Editors and Affiliations

  1. Klinikum der Stadt Ludwigshafen, Bremserstraße 79, 67063, Ludwigshafen, Germany

    K. Schönleben (Präsident des 118. Kongresses der Deutschen Gesellschaft für Chirurgie, Direktor der Chirurgischen Klinik) (Präsident des 118. Kongresses der Deutschen Gesellschaft für Chirurgie, Direktor der Chirurgischen Klinik)

  2. II. Chirurgischer Lehrstuhl Universität zu Köln, Ostmerheimer Straße 200, 51109, Köln, Germany

    E. Neugebauer (Vorsitzender der Sektion Chirurgische Forschung, Leiter der Biochemischen und Experimentellen Abteilung) (Vorsitzender der Sektion Chirurgische Forschung, Leiter der Biochemischen und Experimentellen Abteilung)

  3. Luisenstraße 58/59, 10117, Berlin, Germany

    W. Hartel (Generalsekretär der Deutschen Gesellschaft für Chirurgie) (Generalsekretär der Deutschen Gesellschaft für Chirurgie)

  4. Universität des Saarlandes, 66421, Homburg/Saar, Germany

    M. D. Menger (Direktor der Abteilung für Klinisch-Experimentelle Chirurgie) (Direktor der Abteilung für Klinisch-Experimentelle Chirurgie)

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© 2001 Springer-Verlag Berlin Heidelberg

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Kuntz, C., Schwalbach, P., Schmeding, M., Herfarth, C. (2001). Die Alteration des Stress- und Immunsystems bei laparoskopischen Operationen wird entscheidend von der Art des Eingriffes beeinflusst. In: Schönleben, K., Neugebauer, E., Hartel, W., Menger, M.D. (eds) Chirurgisches Forum 2001 für experimentelle und klinische Forschung. Deutsche Gesellschaft für Chirurgie, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56698-1_137

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  • DOI: https://doi.org/10.1007/978-3-642-56698-1_137

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41718-7

  • Online ISBN: 978-3-642-56698-1

  • eBook Packages: Springer Book Archive

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