Abstract
Titanium is a biomedical material, which has been investigated in different types of tissues and used in a large number of applications (Part V, Chapters 21–27). It is therefore a suitable reference material in studies focused on the mechanisms of integration of materials. As previously reviewed and discussed (Part III, Chapters 7–13), titanium is a material, which is amenable to a large number of modifications. These include surface modifications intended for systematic studies of the biological effects of specific surface properties, a course which has been pursued by us and others. Titanium is also an interesting material to use in combination with other materials with different properties, such as coatings of various types. The most important aspect to be discussed in the following biologically oriented chapters is that titanium has documented and beneficial properties in a biological environment during long-term clinical follow-ups. On the other hand, implanted medical devices may fail, and so do occasionally implants made of titanium. An understanding of the mechanisms, which determine a clinically successful medical device as well as the processes, which lead to such failures is of crucial importance for the future development of safe and functional implants.
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Holgers, KM., Esposito, M., Källtorp, M., Thomsen, P. (2001). Titanium in Soft Tissues. In: Titanium in Medicine. Engineering Materials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56486-4_16
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