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Proteins at Titanium Interfaces

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Titanium in Medicine

Part of the book series: Engineering Materials ((ENG.MAT.))

Abstract

Proteins in solutions accumulate spontaneously at interfaces. Exceptions to this rule may be charge neutral surfaces with high water retention and/or high mobility. In the human body, cell membranes in general, albumin associating cell surfaces, and mucosas with high oligosaccharide content behave in this manner. In vitro, artificial surfaces, such as the charge-neutral poly(ethyleneoxide/-glycols) type of surfaces are protein repellent in one or a few protein systems. However, rigid surfaces like oxide-covered titanium adsorb proteins within seconds of exposure to e.g. blood plasma.

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Authors and Affiliations

  1. Laboratory of Applied Physics, Linköping University, Linköping, Sweden

    Pentti Tengvall

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  1. Pentti Tengvall
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© 2001 Springer-Verlag Berlin Heidelberg

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Tengvall, P. (2001). Proteins at Titanium Interfaces. In: Titanium in Medicine. Engineering Materials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56486-4_14

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  • DOI: https://doi.org/10.1007/978-3-642-56486-4_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63119-1

  • Online ISBN: 978-3-642-56486-4

  • eBook Packages: Springer Book Archive

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