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Molekularmedizinische Grundlagen von nicht-hereditären Tumorerkrankungen pp 257–289Cite as

Nierenzellkarzinome

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Part of the book series: Molekulare Medizin ((MOLMED))

Zusammenfassung

Das Nierenzellkarzinom wurde bereits im frühen 19. Jahrhundert beschrieben und sein Ursprung dem tubulären Epithel zugeordnet. Zunächst setzte sich, aufbauend auf den Arbeiten von Grawitz (1883), die Lehrmeinung durch, dass das Nierenzellkarzinom aus ektopen adrenalen Zellen im Nierengewebe abzuleiten sei, da sich die Karzinomzellen in ihrem Fettgehalt nicht von Zellen der Nebenniere unterscheiden (Grawitz 1883). In der älteren Literatur wird daher das Nierenzellkarzinom auch als Grawitz-Tumor oder hypernephroides Karzinom bezeichnet (Grawitz 1883). Auch der Begriff des Hypernephroms wurde in diesem Zusammenhang geprägt und findet sich fortan zwar konzeptionell falsch, aber dennoch nachhaltig auch heute noch in Lehrbüchern.

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  1. Jochen Decker
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Decker, J., Brauch, H. (2002). Nierenzellkarzinome. In: Ganten, D., Ruckpaul, K., Hahn, S.A., Schmiegel, W. (eds) Molekularmedizinische Grundlagen von nicht-hereditären Tumorerkrankungen. Molekulare Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56297-6_9

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