Minisatellite and Microsatellite DNA Fingerprinting
Most DNA-based inventions receive much media attention, but have little to show in the end by way of practical outcome. One major exception is DNAfingerprinting and the subsequent variations in mini/microsatellite applications. The discovery of minisatellite DNA fingerprinting by A. Jeffreys in 1985 (Jeffreys et al. 1985a, Jeffreys et al. 1985b) in one brief step revolutionised the way forensic science and police casework is performed, and became the norm for the determination of relationships for both humans and animals.
KeywordsShort Tandem Repeat Short Tandem Repeat Locus Forensic Casework Short Tandem Repeat Profile Mini Satellite
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- Home Office (1988) DNA profiling in immigration casework: report of a pilot trial by the Home Office and Foreign and Commonwealth Office. Home Office, LondonGoogle Scholar
- Nyborn H, Schaal BA (1990) DNA “fingerprints” applied to paternity analysis in apples. Theor Appl Genet 79:763–768Google Scholar
- Thomson JA, Ayres KL, Pilotti V, Barrett MN, Walker JIH, Debenham PG (2000) Validation of multiplex STR systems for the investigation of parentage and other familial relationships. In: Sensabaugh GF, Lincoln PJ, Olaisen B (eds) Progress in forensic genetics. Elsevier Science, Amsterdam, pp 374–376Google Scholar
- Walsh PS, Metzger DA, Higuchi R (1992) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques 10:506–513Google Scholar