Kollagen-modifizierte Hydroxylapatit-Implantate führen zu einem erhöhten Knochenremodeling in der Rattentibia

  • Stefan Rammelt
  • E. Schulze
  • M. Witt
  • E. Petsch
  • M. Holch
  • W. Pompe
  • H. Zwipp
Conference paper
Part of the Deutsche Gesellschaft für Chirurgie book series (DTGESCHIR, volume 31)

Abstract

In a rat tibia model bone remodeling was increased around collagen-containing hydroxyapatite bone substitutes as compared with pure HA as measured by increased immunoreactivity against cathepsin D and ED 1 in the early remodeling phase as well as increased immunostaining for extracellular matrix proteins (CD 44, osteopontin).

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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Stefan Rammelt
    • 1
    • 4
  • E. Schulze
    • 1
  • M. Witt
    • 2
  • E. Petsch
    • 1
  • M. Holch
    • 1
  • W. Pompe
    • 3
  • H. Zwipp
    • 1
  1. 1.Klinik und Poliklinik für Unfall- und WiederherstellungschirurgieGermany
  2. 2.Institut für AnatomieUniversitätsklinikum „Carl Gustav Carus“Germany
  3. 3.Institut für WerkstoffwissenschaftenTechnische Universität DresdenGermany
  4. 4.Klinik und Poliklinik für Unfall- und Wiederherstellungschirurgie, Universitätsklinikum „Carl Gustav Carus“Technische Universität DresdenDresdenGermany

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