Timing and Criteria for Beginning Weaning
Mechanical ventilation (MV) is a supportive tool for critically ill patients which saves lives worldwide each day. Nevertheless, this advantage is obtained at the cost of additional morbidity and mortality. The classical side effects of MV are widely recognized in the form of tracheal damage, need for sedatives, and hemodynamic disturbances. In the 1980s, the impact of pulmonary infections, so-called ventilator-associated pneumonia, was the target of substantial research in the field of adverse consequences of MV. In the 1990s, the focus was directed to the direct damage caused by MV on the lungs, and such terms as “barotrauma”,“volotrauma”, and recently “biotrauma” were tailored to define different problems directly related to the use of life-saving MV.
KeywordsFatigue Phosphorus Magnesium Ischemia Pneumonia
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