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Human Infection with Arenaviruses in the Americas

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Book cover Arenaviruses I

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 262))

Abstract

Numerous arenaviruses exist in the Americas as parasites of rodents belonging to the family Muridae, subfamily Sigmodontinae, 14 have been described (Buchmeier et al. 2001; Bowen et al. 1997). Little is known about how these viruses interact with their rodent hosts and what diseases are caused when the viruses spill over into humans. In addition, the Americas host one Old World arenavirus, Lymphocytic choriomeningitis virus, which was introduced in post-Columbian times with its host, Mus musculus.

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References

  • Ambrosio AM, Enria DA, Maiztegui JI (1986) Junin virus isolation from lympho-mononuclear cells of patients with Argentine hemorrhagic fever. Intervirology 25:97–102

    Article  PubMed  CAS  Google Scholar 

  • Andrews BS, Theofilopoulos AN, et al. (1978) Replication of dengue and Junin viruses in cultured rabbit and human endothelial cells. Infect Immun 20:776–781

    PubMed  CAS  Google Scholar 

  • Aronson JF, Herzog NK, Jerrells TR (1994) Pathological and virological features of arenavirus disease in guinea pigs — comparison of two Pichinde virus strains. Am J Pathol 145:228–235

    PubMed  CAS  Google Scholar 

  • Aronson JF, Herzog NK, Jerrells TR (1995) Tumor necrosis factor and the pathogenesis of Pichinde virus infection in guinea pigs. Am J Tropical Med Hyg 52:262–269

    CAS  Google Scholar 

  • Arribalzaga RA (1955) Una nueva enfermedad epidemica a germen desconocido: hipertermia, nefrotoxica, leucopenica y enantematica. Dia Medico (Buenos Aires) 27:1204–1210

    CAS  Google Scholar 

  • Barrera-Oro JG, Eddy GE (1982) Characteristics of candidate live attenuated Junin virus vaccine. In: Kurstak E, Marusyk RG, Maramorosch K (eds) Fourth International Conference on Comparative Virology, Banff, Canada, 17-22 October 1982 (abstract S4-10)

    Google Scholar 

  • Barrera-Oro JG, Lupton HW, et al. (1988) Cross-protection against Machupo virus with Candid #1 live-attenuated Junin virus vaccine. I. The postvaccination prechallenge immune response. Second International Conference on the Impact of Viral Diseases on the Development of Latin American

    Google Scholar 

  • Countries and the Caribbean Region, Buenos Aires, Argentina, 20-26 March 1988

    Google Scholar 

  • Barry M, Russi M, Armstrong L, Geller D, Tesh R, Dembry L, Gonzalez JP, Khan AS, Peters CJ (1995) Treatment of a laboratory-acquired Sabia virus infection. New Engl J Med 333:294–296

    Article  PubMed  CAS  Google Scholar 

  • Barton LL, Hyndman NJ (2000) Lymphocytic choriomeningitis virus: reemerging central nervous system pathogen. Pediatrics. 105:E351–E352

    Article  Google Scholar 

  • Bowen MD, Peters CJ, Nichol ST (1996) The phylogeny of New World (Tacaribe complex) arenaviruses. Virology 219:285–290

    Article  PubMed  CAS  Google Scholar 

  • Bowen MD, Peters CJ, Nichol ST (1997) Phylogenetic analysis of the Arenaviridae: patterns of virus evolution and evidence for cospeciation between arenaviruses and their rodent hosts. Mol Phylogenetics Evolution 8:301–316

    Article  CAS  Google Scholar 

  • Briggiler AM, Levis S, Enria D, Ambrosio AM, Maiztegui JI (1990) Argentine hemorrhagic fever in pregnant women. Medicina (Buenos Aires) 50:443

    Google Scholar 

  • Buchmeier M, Rawls W (1977) Variation between strains of hamsters in the lethality of Pichinde virus infections. Infect Immun 16:413–21

    PubMed  CAS  Google Scholar 

  • Buchmeier MJ, Adam E, Rawls WE (1974) Serologic evidence of infection by Pichinde virus among laboratory workers. Infect Immun 9:821–823

    PubMed  CAS  Google Scholar 

  • Buchmeier MJ, Bowen MD, Peters CJ (2001) Arenaviridae: the viruses and their replication. In: Field Virology, 4th edn. (in press)

    Google Scholar 

  • CDC (2000) Fatal illnesses associated with a New World arenavirus — California, 1999-2000. MMWR 49:709–711

    Google Scholar 

  • Child PL, MacKenzie RB, Johnson KM (1967) Bolivian hemorrhagic fever. A pathologic description. Arch Pathol 83:434–445

    PubMed  CAS  Google Scholar 

  • Coimbra TLM, Nassar ES, Burattini MN, Souza LT de, Ferreira IB, Rocco IM, Travassos da Rosa AP, Vasconcelos PFC, Pinheiro FP, LeDuc JW, Rico-Hesse R, Gonzalez JP, Jahrling PB, Tesh RB (1994) New arenavirus isolated in Brazil. Lancet 343:391–392

    Article  PubMed  Google Scholar 

  • De Bracco MME, Rimolldi MT, Cossio PM, Rabinovich A, Maiztegui J, Carballal G, Arana RM (1978) Argentive hemorrhagic fever. Alterations of the complement system and anti-Junin virus humoral response. N Engl J Med 209:216

    Article  Google Scholar 

  • Douglas RG, Wiebenga NH, Couch RB (1965) Bolivian hemorrhagic fever probably transmitted by personal contact. Am J Epidemiol 82:85–91

    Google Scholar 

  • Eisner B, Schwarz ER, Mando OG, Maiztegui JI, Vilches AM (1973) Pathology of 12 fatal cases of Argentine hemorrhagic fever. Am J Trop Med Hyg 22:229–236

    Google Scholar 

  • Enria D, Maiztegui JI (1994) Antiviral treatment of Argentine hemorrhagic fever. Antivir Res 23:23–31

    Article  PubMed  CAS  Google Scholar 

  • Enria DA, Damilano AJ de, Briggiler AM, Ambrosio AM, Fernandez NJ, Feuillade MR, Maiztegui JI (1985) Sindrome neurologico tardio en enfermos de fiebre hemorragica Argentina tratados con plasma immune. Medicina (Buenos Aires) 45:615–620

    CAS  Google Scholar 

  • Genovesi EV, Peters CJ (1987) Susceptibility of inbred Syrian hamsters (Mesocricetus auratus) to lethal disease by lymphocyte choriomeningitis virus (42541). Proc Soc Exp Biol Med 185:250–261

    PubMed  CAS  Google Scholar 

  • Harrison LH, Halsey NA, McKee KT Jr, Peters CJ, Barrera-Oro JG, Briggiler AM, Feuillade MR, Maiztegui JI (1999) Clinical case definitions for Argentine hemorrhagic fever. Clin Infect Dis 28:1091–1094

    Article  PubMed  CAS  Google Scholar 

  • Heller MV, Saavedra MC, Falcoff R, Maiztegui JI, Molinas FC (1992) Increased tumor necrosis factoralpha levels in Argentine hemorrhagic fever [letter]. J Infect Dis 166:1203–1204

    Article  PubMed  CAS  Google Scholar 

  • Heller MV, Marta RF, Sturk A, Maiztegui JI, Hack CE, Cate JW ten, Molinas FC (1995) Early markers of blood coagulation and fibrinolysis activation in Argentine hemorrhagic fever. Thrombosis Hemostasis 73:368–373

    CAS  Google Scholar 

  • Johnson KM, Kuns ML, Mackenzie RB, Webb PA, Yunker CE (1966) Isolation of Machupo virus from wild rodent Calomys callosus. Am J Trop Med Hyg 15:103–106

    PubMed  CAS  Google Scholar 

  • Johnson KM, Halstead SB, Cohen SN (1967) Hemorrhagic fevers of South-east Asia and South America: a comparative appraisal. Progr Med Virol 9:105–158

    CAS  Google Scholar 

  • Kenyon RH, Peters CJ (1986) Cytolysis of Junin infected target cells by immune guinea pig spleen cells. Microbial Pathogenesis 1:453–464

    Article  PubMed  CAS  Google Scholar 

  • Kenyon RH, McKee KT Jr, et al. (1986) Heterogeneity of Junin virus strains. Med Microbiol Immunol 175:165–167

    Article  Google Scholar 

  • Kenyon RH, Condie RM, et al. (1990) Protection of guinea pigs against experimental Argentine hemorrhagic fever by purified human IgG: importance of elimination of infected cells. Microbial Pathogenesis 9:219–226

    Article  PubMed  CAS  Google Scholar 

  • Kenyon RH, McKee KT Jr, Zack PM, Rippy MK, Vogel AP, York C, Meegan J, Crabbs C, Peters CJ (1992) Aerosol infection of rhesus macaques with Junin virus. Intervirology 33:23–31

    PubMed  CAS  Google Scholar 

  • Kilgore PE, Peters CJ, Mills JN, Rollin PE, Armstrong L, Khan AS, Ksiazek TG (1995) Prospects for the control of Bolivian hemorrhagic fever. Emerg Infect Dis 1:97–100

    Article  PubMed  CAS  Google Scholar 

  • Kilgore PE, Ksiazek TG, Rollin PE, Mills JN, Villagra MR, Montenegro MJ, Costales MA, Paredes LC, Peters CJ (1997) Treatment of Bolivian hemorrhagic fever with intravenous ribavirin. J Infect Dis 24:718–722

    Article  CAS  Google Scholar 

  • Kosoy MY, Elliott LH, Ksiazek TG, Fulhorst CF, Rollin PE, Childs JE, Mills JN, Maupin GO, Peters CJ (1996) Prevalence of antibodies to arenaviruses in rodents from the southern and western United States: evidence for an arenavirus associated with the genus Neotoma. Am J Trop Med Hyg 54: 570–576

    PubMed  CAS  Google Scholar 

  • Levis SC, Saavedra MC, Ceccoli C, Feuillade MR, Enria DA, Maiztegui JI, Falcoff R (1985) Correlation between endogenous interferon and the clinical evolution of patients with Argentine hemorrhagic fever. J Interferon Res 5:383–389

    Article  PubMed  CAS  Google Scholar 

  • Liu CT, Jahrling PB, Peters CJ (1986) Evidence for the involvement of sulfidopeptide leukotrienes in the pathogenesis of Pichinde virus infection in strain 13 guinea pigs. Prostaglandins Leukotrienes Med 24:129–138

    Article  CAS  Google Scholar 

  • Lozano ME, Enria D, Maiztegui JI, Grau O, Romanowski V (1995) Rapid diagnosis of Argentine hemorrhagic fever by reverse transcriptase PCR-based assay. J Clin Microbiol 33:1327–1332

    PubMed  CAS  Google Scholar 

  • Maiztegui JI, McKee KT, Barrera-Oro JG, Harrison LH, Gibbs PH, Feuillade MR, Enria DA, Briggiler AM, Levis SC, Ambrosio AM, Halsey NA, Peters CJ, and the AHF Study Group (1998) Protective efficacy of a live attenuated vaccine against Argentine hemorrhagic fever. J Infect Dis 177:277–283

    Article  PubMed  CAS  Google Scholar 

  • Manzione N de, Salas RA, Paredes H, Godoy O, Rojas L, Araoz F, Fulhorst CF, Ksiazek TG, Mills JN, Ellis BA, Peters CJ, Tesh RB (1998) Venezuelan hemorrhagic fever: clinical and epidemiologic studies of 165 cases. Clin Infect Dis 26:308–313

    Article  PubMed  Google Scholar 

  • Marta RF, Montero VF, et al. (1999) Proinflammatory cytokines and elastase-alpha-1 antitrypsin in Argentine hemorrhagic fever. Am J Trop Med Hyg 60:85–89

    PubMed  CAS  Google Scholar 

  • McKee KT, Mahlandt BG, et al. (1985) Experimental Argentine hemorrhagic fever in rhesus macaques: viral strain-dependent clinical response. J Infect Dis 152:218–221

    Article  PubMed  Google Scholar 

  • Mercado RR (1975) Rodent control programmes in areas affected by Bolivian haemorrhagic fever. Bull World Health Org 52:691–696

    PubMed  CAS  Google Scholar 

  • Mills JN, Ellis BA, McKee KT, Calderon GE, Maiztegui JI, Nelson GO, Ksiazek TG, Peters CJ, Childs JE (1992) A longitudinal study of Junin virus activity in the rodent reservoir of Argentine hemorrhagic fever. Am J Trop Med Hyg 47:749–763

    PubMed  CAS  Google Scholar 

  • Mills JN, Ellis BA, et al. (1994) Prevalence of infection with Junin virus in rodent populations in the epidemic area of Argentine hemorrhagic fever. Am J Trop Med Hyg 51:554–562

    PubMed  CAS  Google Scholar 

  • Molinas FC, Bracco MME de, Maiztegui JI (1989) Hemostasis and the complement system in Argentine hemorrhagic fever. Rev Infect Dis 11 [Suppl 4]:762–767

    Article  Google Scholar 

  • Molteni HD, Guarinos HC, Petrillo CO, Jaschek FRJ (1961) Estudio clinico estadistico sobre 338 pacientes afectados por la fiebre hemorragica epidemica del Noroeste de la Provincia de Buenos Aires. Semana Med 118:838–855, 878

    Google Scholar 

  • Parisi MDN, Enria DA, Pini NC, Sabattini MS (1996) Retrospective detection of clinical infections caused by hantavirus in Argentina. Medicina (Buenos Aires) 56:1–13

    Google Scholar 

  • Parodi AS, Greenway DJ, Rugiero HR, Rivero E, Frigerio MJ, Barrera JM de la, Mettler NE, Garzon F, Boxaca MC, Guerrero LB, Nota NR (1958) Sobre la etiologia del brote epidemico de Junin (Nota previa). Dia Medico 30:62

    Google Scholar 

  • Peters CJ (1997) Pathogenesis of viral hemorrhagic fevers. In: Nathanson N, Ahmed R, Gonzalez-Scarano F, Griffin D, Holmes KV, Murphy FA, Robinson HL (eds) Viral pathogenesis. Lippincott-Raven, Philadelphia, pp 779–799

    Google Scholar 

  • Peters CJ, Webb PA, Johnson KM (1972) Measurement of antibodies to Machupo virus by the indirect fluorescent technique. Proc Soc Exp Biol Med 142:526–531

    Google Scholar 

  • Peters CJ, Kuehne RW, et al. (1974) Hemorrhagic fever in Cochabamba, Bolivia, 1971. Am J Epidemiol 99:425–433

    PubMed  CAS  Google Scholar 

  • Peters CJ, Jahrling PB, et al. (1987) Experimental studies of arenaviral hemorrhagic fevers. In: Oldstone MB (ed) Current Topics in Microbiology and Immunology, Vol 134. Arenaviruses: epidemiology and immunotherapy. Springer Verlag, Berlin Heidelberg New York, pp 5–68

    Google Scholar 

  • Peters CJ, Zaki SR, Rollin PE (1997) Viral hemorrhagic fevers. In: Fekety R (ed) Atlas of infectious diseases, Vol 8. External manifestations of systemic infections. Current Medicine, Philadelphia, pp 10.1–10.26

    Google Scholar 

  • Peters CJ, Simpson GL, Levy H (1999) Spectrum of hantavirus infection: hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Annu Rev Med 50:531–545

    Article  PubMed  CAS  Google Scholar 

  • Pinheiro FP, Woodall JP, Travassos da Rosa PA, Travassos da Rosa JF (1977) Studies on arenaviruses in Brazil. Medicina (Buenos Aires) 37:175–181

    Google Scholar 

  • Pirosky I, Zuccarini J, Molinelli EA, Di Pietro A, Barrera-Oro JG, Martini P, Capello AR (1959) Virosis hemorragica del noroeste bonaerense (endemo-epidemica, febril, enantematica y leucopenica). Buenos Aires Instituto Nacional de Microbiologia, Minesterio de Asistencia Social y Salud Publica

    Google Scholar 

  • Qian C, Jahrling PB, Peters CJ, Liu CT (1994) Cardiovascular and pulmonary responses to Pichinde virus infection in strain 13 guinea pigs. Lab Animal Sci 44:600–607

    CAS  Google Scholar 

  • Ruggiero HR, Cintora FA, Libonatti EJ, Magnoni CC, Castiglione EB, Locicero R (1960) Formas nerviosas de la fiebre hemorragica epidemica. Prensa med argent 47:1845–1849

    Google Scholar 

  • Ruggiero HR, Ruggiero H, Gonzalez-Cambaceres C, Cintora FA, Maglio F, Magnoni CC, Astarloa LN, Squassi GJ, Giacosa A, Fernandez D (1964) Argentine hemorrhagic fever. II. Clinical studies. Rev Asoc Med Argentina 78:281–294

    Google Scholar 

  • Salas R, Manzione N de Tesh RB, Rico-Hesse R, Shope RE, Betaucourt A, Godoy O, Bruzual R, Pacheco DE, Ramos B, Taibo ME, Tamayo JG, James E, Vasquez C, Araoz F, Querales J (1991) Venezuelan hemorrhagic fever. Lancet 338:1033–1036

    Article  PubMed  CAS  Google Scholar 

  • Stephen EL, Jones DE, et al. (1980) Ribavirin treatment of toga-, arena-, and bunyavirus infections in subhuman primates and other laboratory animal species. In: Smith RA, Kirkpatrick W (eds) Ribavirin: a broad spectrum antiviral agent. Academic Press, New York, pp 169–183

    Google Scholar 

  • Stinebaugh BJ, Schloeder FX, Johnson KM, et al. (1966) Bolivian hemorrhagic fever: a report of four cases. Am J Med 40:217

    Article  PubMed  CAS  Google Scholar 

  • Tesh RB, Jahrling PB, Salas R, Shope RE (1994) Description of Guanarito virus (Arenaviridae: Arenavirus), the etiologic agent of Venezuelan hemorrhagic fever. Am J Trop Med Hyg 50:452–459

    PubMed  CAS  Google Scholar 

  • Vallejos DA, Ambrosio AM, Feuillade MR, Maiztegui JI (1989) Lymphocyte subsets alteration in patients with Argentine hemorrhagic fever. J Med Virol 27:160–163

    Article  PubMed  CAS  Google Scholar 

  • Zaki SR, Peters CJ (1997) Viral hemorrhagic fevers. In: Connor DH, Chandler FW, Schwartz DA, Manz HJ, Lack EE (eds) The pathology of infectious diseases. Appleton and Lange, Norwalk, Conn., pp 347–364

    Google Scholar 

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Peters, C.J. (2002). Human Infection with Arenaviruses in the Americas. In: Oldstone, M.B.A. (eds) Arenaviruses I. Current Topics in Microbiology and Immunology, vol 262. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56029-3_3

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  • DOI: https://doi.org/10.1007/978-3-642-56029-3_3

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