Zusammenfassung
In diesem Kapitel sollen gegenwärtig zur Anwendung kommende operative Behandlungskonzepte des Lymphabflusses bei malignen Kopf-Hals-Tumoren diskutiert werden. Die zu dieser Thematik vorliegende Vielzahl gegensätzlicher Literaturmitteilungen drückt die Uneinheitlichkeit der operativen Behandlungsstrategien bei zuvor genannter Indikation aus. Diese Problematik erklärt sich nicht zuletzt durch zahlreiche, mittlerweile mehr oder weniger anerkannte Varianten der Neck dissection, die in der Zwischenzeit um zusätzliche, so genannte limitierte selektive Neck-dissection-Formen (z.B. isolierte Ausräumung der Regionen II und III beim Pharynxkarzinom beim Nooder auch N+-Hals) ergänzt wurden. Eben dieses breite Behandlungsspektrum macht es zum gegenwärtigen Zeitpunkt sehr schwierig, einen allgemein gültigen Vorschlag zur Therapie des Lymphabflusses bei Kopf-Hals-Malignomen zu erarbeiten. So gilt es zunächst, nach onkologischen Gesichtspunkten anerkannte Behandlungsvorschläge zur operativen Therapie des No-Halses, des N+-Halses sowie von Lymphknotenmetastasen bei unbekanntem Primärtumor zu erfassen und auf deren Grundlage eine Diskussion mit den erwähnten, im Behandlungsausmaß reduzierten chirurgischen Konzepten zu führen.
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Literatur
Ambrosch P, Freudenberg L, Kron M, Steiner W (1996) Selective neck dissection in the management of squamous cell carcinoma of the upper digestive tract. Eur Arch Otorhinolaryngol 253: 329–335
Ambrosch P, Kron M, Pradier O, Steiner W (2001) Efficacy of selective neck dissection: A review of 503 cases of elective and therapeutic treatment of the neck in squamous cell carcinoma of the upper aerodigestive tract. Otolaryngol Head Neck Surg 124: 180–187
Bataini JP (1993) Radiotherapy in No head and neck cancer patients. Eur Arch Otorhinolaryngol 250: 442–445
Batsakis JQ (1979) Squamous cell carcinomas of the oral cavity and the oropharynx. In: Batsakis JG (ed ) Tumors of the head and neck: Clinical and pathological considerations, 2nd edn. Williams & Wilkins, Baltimore, pp 144–176
Boysen M, Lovdal O, Natvig K, Tausjo J, Jacobsen AB, Evensen JF (1992) Combined radiotherapy and surgery in the treatment of neck node metastases from squamous cell carcinoma of the head and neck. Acta Oncol 31: 455–460
Chen WZ, Zhou DL, Luo KS (1989) Long-term observation after radiotherapy for nasopharyngeal carcinoma (NPC). Int Radiat Oncol Biol Phys 16: 311–314
Choe W, Housini I, Mello AM (1995) Lymphoscintigraphy in a case of Merkel cell tumor. Clin Nucl Med 20: 922–924
Cunningham MJ, Johnson JT, Myers EN (1986) Cervical lymph node metastasis after local excision of early squamous cell carcinoma of the oral cavity. Am J Surg 152: 361–366
DeSanto LW, Magrina C, O’Fallon WM (1990) The „second“side of the neck in supraglottic cancer. Otolaryngol Head Neck Surg 102: 351–361
Duenne AA, Werner JA (2000) Functional anatomy of lymphatic vessels under the aspect of tumor invasion. Recent Results Cancer Res 157: 82–89
Eckel HE (2001) Peristomal recurrences of laryngeal and hypopharyngeal carcinoma. In: Lippert BM, Werner JA (eds) Metastases in head and neck cancer. Tectum, Marburg, PP 389–394
Fakih AR, Rao RS, Borges AM, Patel AR (1989) Elective versus therapeutic neck dissection in early carcinoma of the oral tongue. Am J Surg 158: 309–313
Ganzer U, Meyer-Breiting E, Ebbers J, Vosteen KH (1982) Der Einfluss von Tumorgröße, Lympknotenbefall und Behandlungsart auf die Prognose des Hypopharynxkarzinoms. Laryngorhinootologie 61:622–628
Gavilán C, Gavilán J (1989) Five-year results of functional neck dissection for cancer of the larynx. Arch Otolaryngol Head Neck Surg 115: 1193–1196
Gavilán J, Gavilán C, Herranz J (1994) The neck in supraglot tic cancer. In: Smee R, Bridger GP (eds) Laryngeal cancer. Elsevier, Amsterdam, pp 576–581
Gimm O, Dralle H (1997) Reoperation in metastasing medullary thyroid carcinoma: Is tumor stage-oriented approach justified? Surgery 122: 1124–1130
Gimm O, Ukkat J, Dralle H (1998) Determinative factors of biochemical cure after primary and reoperative surgery for sporadic medullary thyroid carcinoma. World J Surg 22: 562–567
Gluckman JL, Hamaker RC, Schuller DE, Weissler MC, Charles GA (1987) Surgical salvage for stomal recurrence: A multi-institutional experience. Laryngoscope 97: 1025–1029
Goretzki P, Simon D, Frilling A (1993) Surgical reinterventon for differentiated thyroid cancer. Br J Surg 80: 1009
Goretzki P,Dotzenrath C (2000) Differenziertes Schilddrüsenkarzinom. In: Rothmund M (Hrsg) Endokrine Chirurgie. Springer, Berlin Heidelberg New York Tokyo, S 1–202
Hauschild A, Lischner S, Christophers E (2000) Surgical and adjuvant drug therapy in head and neck cutaneous melanoma. Laryngorhinootologie 79: 428–433
Ho CM, Lam KH, Wei WI (1992) Occult lymph node metastasis in small oral tongue cancers. Head Neck 14:359–363
Hoppe RT, Goffinet DR, Bagshaw MA (1967) Carcinoma of the nasopharynx: Eighteen years’ experiences with megavoltage radiation therapy. Cancer 37: 2605–2612
Hosal AS, Carrau RL, Johnson JT, Myers EN (2000) Selective neck dissection in the management of the clinically node-negative neck. Laryngoscope 110: 2037–2040
Johnson JT, Bacon GW, Myers EN, Wagner RL (1994) Medial versus lateral wall pyriform sinus carcinoma: Implications for management of regional lymphatics. Head Neck 16: 401–405.
Konno A, Togawa K, Iizuka K (1981) Analysis of factors affecting complication of carotid ligation. Ann Otol Rhinol Laryngol 90: 222–226
Leon X, Quer M, Burgues J, Abello P, Vega M, de Andres L (1996) Prevention of stomal recurrence. Head Neck 18:54–59
Lippert BM, Werner JA (2001) Metastases in head and neck cancer. Tectum, Marburg
Mantravadi R, Katz AM, Skolnik EM, Becker S, Freehling DJ, Friedman M (1981) Stomal recurrence. A critical analysis of risk factors. Arch Otolaryngol 107: 735–738
Moore OS, Karlan M, Sigler L (1969) Factors influencing the safety of carotid ligation. Am J Surg 118: 666–668
Morrison WH, Peters LJ, Silva EG, Wendt CD, Ang KK, Goep-fert H (1990) The essential role of radiation therapy in securing locoregional control of Merkel cell carcinoma. Int J Radiat Oncol Biol Phys 19: 583–591
Netterville JL, Civantos FJ (1994) N3 neck: Optimal therapy. In: Shockley WW, Pillsbury III HC (eds) The neck. Diagnosis and surgery. Mosby, St. Louis, pp 405–411
O’Brien CJ, Petersen-Schaefer K, Ruark D, Coates AS, Menzie SJ, Harrison RI (1995) Radical, modified, and selective neck dissection for cutaneous malignant melanoma. Head Neck 17: 232–241
Rabuzzi DD, Chung CT, Saagerman RH (1980) Prophylactic neck irradiation. Arch Otolaryngol Head Neck Surg 106:454–455
Regine WF, Patchell RA, Strottmann JM, Meigooni A, Sanders M, Young B (2000) Combined stereotactic split-course fractionated gamma knife radiosurgery and conventional radiation therapy for unfavorable gliomas: A phase I study. J Neurosurg 93: 37–41
Robbins KT (1999) Targeted cisplatin chemotherapy for advanced head and neck cancer. In: Eckert A (ed) Intra-arterial chemotherapy in head and neck cancer. Current results and future perspectives. Einhorn, New York, pp 173–182
Robbins KT, Woodson GE (1985) Thyroid carcinoma presenting as a parapharyngeal mass. Head Neck Surg 7: 434–436
Robbins KT, Storniolo AM, Hryniuk WM, Howell SB (1996) „Decadose“ effects of cisplatin on squamous cell carcinoma of the upper aerodigestive tract. II. Clinical studies. Laryngoscope 106: 37–42
Robbins KT, Wong FS, Kumar P, Hartsell WF, Vieira F, Mullins B, Niell HB (1999) Efficacy of targeted chemoradiation and planned selective neck dissection to control bulky nodal disease in advanced head and neck cancer. Arch Otolaryngol Head Neck Surg 125: 670–675
Rockley TJ, Powell J, Robin PE, Reid AP (1991) Post-laryn-gectomy stomal recurrence: Tumour implantation or paratracheal lymphatic metastasis? Clin Otolaryngol 16: 43–47
Röher HD, Simon D, Sitte J, Goretzki P (1994) Principals of limited or radical surgery for differentiated thyroid cancer. Thyroidology 5: 93
Rubin J, Johnson JT, Myers EN (1990) Stomal recurrence after laryngectomy: Interrelated risk factor study. Otolaryngol Head Neck Surg 103: 805–812
Samant S, Kumar P, Wan J et al. (1999) Concomitant radiation therapy and targeted cisplatin chemotherapy for the treatment of advanced pyriform sinus carcinoma: Disease control and preservation of organ function. Head Neck 21: 595–601
Scherer H (1984) Behandlungsmöglichkeiten des malignen Melanoms des Gaumens, der Nasenhöhle und der Nasennebenhöhlen. Laryngorhinootologie 63: 9–10
Sisson GA (1989) Ogura memorial lecture: Mediastinal dissection. Laryngoscope 99: 1262–1266
Schobel G, Hollmann K, Millesi W (1992) Über das Risiko der Mitresektion der Arteria carotis communis bzw. interna bei der Exstirpation von Tumoren im maxillo-facialen Bereich. In: Vinzenz K, Waclawiczek HW (Hrsg) Chirurgische Therapie von Kopf-Hals-Karzinomen. Springer, Wien, S 269–282
Sian KU, Wagner JDW, Sood R, Park HM, Havlik R, Coleman JJ (1999) Lymphoscitigraphy with sentinel lymph node biopsy in cutaneous merkel cell carcinoma. Ann Plast Surg 42: 679–688
Singletary SE, Byers RM, Shallenberger R, McBride CM, Guinee UF (1986) Prognostic factors in patients with regional cervical nodal metastases from cutaneous malignant melanoma. Am Surg 152: 371–375
Steiner W (1984) Surgical treatment of the cervical lymph node system in laryngeal carcinoma. In: Wigand ME, Steiner W, Stell PM (eds) Functional partial laryngectomy. Springer, Berlin Heidelberg New York Tokyo, pp 253–264
Steiner W, Hommerich CP (1993) Diagnosis and treatment of the No neck of carcinomas of the upper aerodigestive tract. Report of an international symposium, Göttingen, Germany, 1992. Eur Arch Otolaryngol 250: 450–456
Teicher BA, Holden SA, Kelley MJ et al. (1987) Characterization of a human squamous carcinoma cell line resistant to cis-diamminedichloroplatinum(II). Cancer Res 47: 388–393
Teichgraeber JF, Clairmont AA (1984) The incidence of occult metastases for cancer of the oral tongue and floor of the mouth: Treatment rationale. Head Neck 7: 15–21
van den Brekel MW, van der Waal I, Meijer CJ, Freeman JL, Castelijns JA, Snow GB (1996) The incidence of micrometastases in neck dissection specimens obtained from elective neck dissections. Laryngoscope 106: 987–991
Vandenbrouck C, Sancho-Garnier H, Chassagne D, Saravane D, Cachin Y, Micheau C (1980) Elective versus therapeutic radical neck dissection in epidermoid carcinoma of the oral cavity. Results of a randomized clinical trial. Cancer 46: 386–390
Veterans Affairs Laryngeal Cancer Study Group (1991) Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced larnygeal cancer. The Department of Veteran Affairs, Laryngeal Cancer Study Group. N Engl J Med 324: 1685–1690
Victor NS, Blaine M, Smith JW (1996) Merkel cell cancer: Is prophylactic lymph node dissection indicated? Am Surg 62: 879–882
Von Hoff DD, Clark GM, Weiss GR, Marshall MH, Buchok JB,Knight WA 3d, LeMaistre C (1986) Use of in vitro dose response effects to select antineoplastics for high-dose or regional administration regimens. Clin Oncol 4: 1827–1834
Weissler MC (1994) Technique of radical neck dissection. In: Shockley WW, Pillsbury III HC (eds) The neck. Diagnosis and surgery. Mosby, St. Louis, pp 573–588
Werner JA, Schünke M, Rudert H, Tillmann B (1990) Description and clinical importance of the lymphatics of the vocal fold. Otolaryngol Head Neck Surg 102: 13–19
Werner JA, Dünne AA, Lippert, BM (im Druck) Indikationen zur Halsexploration bei nicht nachweisbaren Lymphknotenmetastasen. Teil I. HNO
Werner JA, Dünne AA, Lippert, BM (im Druck) Indikationen zur Halsexploration bei nicht nachweisbaren Lymphknotenmetastasen. Teil IL HNO
Wei WI, Sham JS (1996) Cancer of the nasopharynx. In: Myers EN, Suen JY (eds) Cancer of the head and neck. Philadelphia, Saunders, pp 277–293
Yotakis J, Davris S, Kontozoglou T, Adamopoulos G (1996) Evaluation of risk factors for stomal recurrence after total laryngectomy. Clin Otolaryngol 21: 135–138
Zbaren P, Greiner R, Kengelbacher M (1996) Stoma recurrence after laryngectomy: an analysis of risk factors. Otolaryngol Head Neck Surg 114: 569–575
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Werner, J.A. (2002). Konzept der chirurgischen Behandlung des Lymphabflusses bei malignen Tumoren des Kopf-Hals-Bereiches. In: Lymphknotenerkrankungen im Kopf-Hals-Bereich. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55923-5_11
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