Regulation of HMGCoA Reducíase Activity by Salt Stress in Hortaea werneckii

  • Uroš Petrovič
  • Ana Plemenitaš
Part of the Springer Lab Manuals book series (SLM)


To study the effect of salt stress on sterol biosynthesis through the activity of 3-hydroxy-3-methylglutaryl CoA reductase (HMG R) in halophilic Hortaea werneckii.


Salt Stress Mevalonic Acid Sterol Biosynthesis Geranyl Pyrophosphate Dimethylallyl Pyrophosphate 
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  1. Gunde-Cimerman N, Zalar P, De Hoog S, Plemenitas A (2000) Hypersaline waters in salterns-natural ecological niches for halophilic black yeasts. FEMS Microbiol Ecol 32:235–240Google Scholar
  2. Mejanelle L, Lopez JF, Gunde-Cimerman N, Grimait JO (2001) Ergosterol biosynthesis in novel melanized fungi from hypersaline environments. J Lipid Res 42:352–359PubMedGoogle Scholar
  3. Petrovic U, Gunde-Cimerman N, Plemenitas A (1999) Salt stress affects sterol biosynthesis in the halophilic black yeast Hortaea werneckii. FEMS Microbiol Lett 180:325–330PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Uroš Petrovič
    • 1
  • Ana Plemenitaš
    • 2
  1. 1.Department of Biochemistry and Molecular BiologyInstitute of Jozef StefanLjubljanaSlovenia
  2. 2.Institute of BiochemistryUniversity of Ljubljana, Faculty of MedicineLjubljanaSlovenia

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