Cancer patients experience episodes of increase in pain on a background of continuous pain. Breakthrough pain is defined as a transitory exacerbation of pain that occurs on a background of otherwise stable pain in a patient receiving chronic opioid therapy (Portenoy and Hagen 1990).
KeywordsBreakthrough Pain Spontaneous Pain Incident Pain Continuous Pain Chronic Opioid Therapy
- Portenoy RK, Messina J, Xie F et al. Fentanyl buccal tablet for relief of breakthrough pain in opioid treated patients with chronic low back pain. Current Medical Research and Opinion 2007;23(1):223–233.Google Scholar