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Systems Biology: Developments and Applications

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Molecular Mechanisms in Yeast Carbon Metabolism

Abstract

Systems biology relies on systems theory concepts and is applicable to both fundamental studies of cellular biology as well as applied research such as metabolic engineering. In this chapter, we map the context of systems biology developments and highlight its contribution in understanding the yeast carbon metabolism. Systems biology not only contributes towards the global overview of metabolism but also in combination with an integrative analysis approach facilitates the elucidation of molecular mechanisms. In particular we discuss the role of systems biology in unraveling the molecular details concerning glucose and galactose metabolism. In conclusion, this chapter provides an overview of the progress and impact of systems biology in carbon metabolism.

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Acknowledgments

We acknowledge financial support from UNICELLSYS and European Research Council.

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Authors and Affiliations

  1. Systems and Synthetic Biology, Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE-41296, Gothenburg, Sweden

    Rahul Kumar, Petri-Jaan Lahtvee & Jens Nielsen

Authors
  1. Rahul Kumar
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  2. Petri-Jaan Lahtvee
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  3. Jens Nielsen
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Corresponding author

Correspondence to Jens Nielsen .

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Editors and Affiliations

  1. Dept. Cell & Organism Biology, University of Lund Fac. Science, Lund, Sweden

    Jure Piškur

  2. Department of Food, Environmental and Nutritional Sciences, University of Milan, Milan, Italy

    Concetta Compagno

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Kumar, R., Lahtvee, PJ., Nielsen, J. (2014). Systems Biology: Developments and Applications. In: Piškur, J., Compagno, C. (eds) Molecular Mechanisms in Yeast Carbon Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55013-3_4

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