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Acquired Hemostatic Disorders

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Perioperative Hemostasis

Abstract

Acquired hemostatic disorders comprise thrombocytopenia and platelet dysfunction, coagulation factor deficiencies, excessive anticoagulation, and hemorrhagic complications due to antiplatelet drugs, anticoagulation, and thrombolysis. Blood disorders associated with myeloproliferative neoplasms and disseminated intravascular coagulation can cause both bleeding and thrombosis. Heparin-induced thrombocytopenia, antiphospholipid antibody syndrome, and thrombotic microangiopathies are conditions that can cause thrombocytopenia, but they are more frequently responsible for thrombosis than for bleeding.

This chapter sets out diagnostic and management strategies for acquired hemostatic disorders, with a particular emphasis on features that can prove useful in a perioperative context. Antiplatelet and anticoagulant drug complications are presented in Chap. 8.

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Authors and Affiliations

  1. Service of Hematology, Lausanne University Hospital (CHUV), CH-1011, Lausanne, Switzerland

    Stefano Barelli, Sabine Blum & Anne Angelillo-Scherrer

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  1. Stefano Barelli
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  2. Sabine Blum
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  3. Anne Angelillo-Scherrer
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Correspondence to Anne Angelillo-Scherrer .

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Editors and Affiliations

  1. Department of Anesthesiology, University Hospital of Lausanne, Lausanne, Switzerland

    Carlo Enrique Marcucci

  2. Department of Anesthesiology, University Hospital of Lausanne, Lausanne, Switzerland

    Patrick Schoettker

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Barelli, S., Blum, S., Angelillo-Scherrer, A. (2015). Acquired Hemostatic Disorders. In: Marcucci, C., Schoettker, P. (eds) Perioperative Hemostasis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55004-1_7

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  • DOI: https://doi.org/10.1007/978-3-642-55004-1_7

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