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Unterstützung bei Lungenversagen

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Die Intensivmedizin

Zusammenfassung

Die Anwendung extrakorporaler Lungenunterstützungsverfahren (ELUV) hat sich zu Ende des letzten Jahrzehnts deutlich gewandelt. Die H1N1-Pandemie hat zu einer deutlichen Steigerung der Anwendung von ECMO-Therapien bei ARDS-Patienten geführt (Terragni et al. 2013; Paden et al. 2013), mit dokumentierten Überlebensraten von >70% (Patroniti et al. 2011; Webb et al. 2009). Durch Weiterentwicklung der Systeme und Therapiestrategien konnten die Komplikationsraten in den vergangenen Jahren deutlich reduziert werden (Terragni et al. 2013; Holzgraefe et al. 2010).

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Literatur

  • Abetz V, Brinkmann T, Dijkstra M, Ebert K, Fritsch D, Ohlrogge K et al (2006) Developments in membrane research: from material via process design to industrial application. Adv Eng Mater 8(5):328–58

    Article  CAS  Google Scholar 

  • Bein T, Zimmermann M, Philipp A, Ramming M, Sinner B, Schmid C et al (2011) Addition of acetylsalicylic acid to heparin for anticoagulation management during pumpless extracorporeal lung assist. ASAIO J 57(3):164–8 (Epub 2011/03/24])

    Article  CAS  PubMed  Google Scholar 

  • Bein T, Weber-Carstens S, Goldmann A, Muller T, Staudinger T, Brederlau J et al (2013) Lower tidal volume strategy ( approximately 3 ml/kg) combined with extracorporeal CO2 removal versus ’conventional’ protective ventilation (6 ml/kg) in severe ARDS: the prospective randomized Xtravent-study. Intensive Care Med 39(5):847–56 (Epub 2013/01/12])

    Article  PubMed Central  PubMed  Google Scholar 

  • Bongert MGM, Pennekamp W, Strauß A, Aschenbrenner U (2012) In silicio Untersuchung der Sauerstoffsättigung im rechten Vorhof in Abhängigkeit der Kanülenpositionierung bei der VV-ECMO Anwendung. Z Herz Thorax Gefäßchir 26(6):1435–1277

    Google Scholar 

  • Brechot N, Luyt CE, Schmidt M, Leprince P, Trouillet JL, Leger P et al (2013) Venoarterial extracorporeal membrane oxygenation support for refractory cardiovascular dysfunction during severe bacterial septic shock. Crit Care Med 41(7):1616–26 (Epub 2013/04/09])

    Article  CAS  PubMed  Google Scholar 

  • Burki NK, Mani RK, Herth FJ, Schmidt W, Teschler H, Bonin F et al (2013) A novel extracorporeal CO (2) removal system: results of a pilot study of hypercapnic respiratory failure in patients with COPD. Chest 143(3):678–86 (Epub 2013/03/06])

    CAS  PubMed Central  PubMed  Google Scholar 

  • Cheng R, Hachamovitch R, Kittleson M, Patel J, Arabia F, Moriguchi J et al (2013) Complications of extracorporeal membrane oxygenation for treatment of cardiogenic shock and cardiac arrest: a meta-analysis of 1,866 adult patients. Ann Thorac Surg. (Epub 2013/11/12)

    Google Scholar 

  • Fallon SC, Shekerdemian LS, Olutoye OO, Cass DL, Zamora IJ, Nguyen T et al (2013) Initial experience with single-vessel cannulation for venovenous extracorporeal membrane oxygenation in pediatric respiratory failure. Pediat Crit Care Med 14(4):366–73 (Epub 2013/04/04])

    Article  Google Scholar 

  • Gattinoni L, Kolobow T, Tomlinson T, White D, Pierce J (1978) Control of intermittent positive pressure breathing (IPPB) by extracorporeal removal of carbon dioxide. Br J Anaesth 50(8):753–8 (Epub 1978/08/01])

    Google Scholar 

  • Hill JD, O’Brien TG, Murray JJ, Dontigny L, Bramson ML, Osborn JJ et al (1972) Prolonged extracorporeal oxygenation for acute post-traumatic respiratory failure (shock-lung syndrome). Use of the Bramson membrane lung. NEJM 286(12):629–34 (Epub 1972/03/23])

    Article  CAS  PubMed  Google Scholar 

  • Hoeper MM, Wiesner O, Hadem J, Wahl O, Suhling H, Duesberg C et al (2013) Extracorporeal membrane oxygenation instead of invasive mechanical ventilation in patients with acute respiratory distress syndrome. Intensive Care Med 39(11):2056–7

    Article  PubMed  Google Scholar 

  • Holzgraefe B, Broome M, Kalzen H, Konrad D, Palmer K, Frenckner B (2010) Extracorporeal membrane oxygenation for pandemic H1N1 2009 respiratory failure. Minerva Anestesiol 76(12):1043–51 (Epub 2010/12/24])

    CAS  PubMed  Google Scholar 

  • Ijland MM, Heunks LM, van der Hoeven JG (2010) Bench-to-bedside review: hypercapnic acidosis in lung injury--from ’permissive’ to ’therapeutic’. Crit Care 14(6):237 (Epub 2010/11/12])

    Article  PubMed  Google Scholar 

  • Kipping V, Weber-Carstens S, Lojewski C, Feldmann P, Rydlewski A, Boemke W et al (2013) Prone position during ECMO is safe and improves oxygenation. Int J Artific Organs 36(11):821–32 (Epub 2013/12/18])

    Article  CAS  Google Scholar 

  • Kluge S, Braune SA, Engel M, Nierhaus A, Frings D, Ebelt H et al (2012) Avoiding invasive mechanical ventilation by extracorporeal carbon dioxide removal in patients failing noninvasive ventilation. Intensive Care Med 38(10):1632–9 (Epub 2012/07/28])

    Article  PubMed  Google Scholar 

  • Lehle K, Philipp A, Muller T, Schettler F, Bein T, Schmid C et al (2013) Flow Dynamics of Different Adult ECMO Systems: A Clinical Evaluation. Artif Organs. (Epub 2013/10/15)

    Google Scholar 

  • Malagon I, Greenhalgh D (2013) Extracorporeal membrane oxygenation as an alternative to ventilation. Curr Opinion Anaesthesiol 26(1):47–52 (Epub 2012/12/25])

    CAS  Google Scholar 

  • Muller T, Lubnow M, Philipp A, Bein T, Jeron A, Luchner A et al (2009) Extracorporeal pumpless interventional lung assist in clinical practice: determinants of efficacy. Eur Respirat J 33(3):551–8 (Epub 2008/11/18])

    Article  CAS  Google Scholar 

  • Munshi L, Fan E, Del Sorbo L (2013) Prone position during ECMO: A turn of events? Minerva Anestesiol. (Epub 2013/12/12)

    Google Scholar 

  • Ohtake S, Kawashima Y, Hirose H, Matsuda H, Nakano S, Kaku K et al (1983) Experimental evaluation of pumpless arteriovenous ECMO with polypropylene hollow fiber membrane oxygenator for partial respiratory support. Trans Am Soc Artif Intern Organs 29:237–41 (Epub 1983/01/01])

    CAS  PubMed  Google Scholar 

  • Paden ML, Conrad SA, Rycus PT, Thiagarajan RR (2013) Extracorporeal Life Support Organization Registry Report 2012. ASAIO J 59(3):202–10 (Epub 2013/05/07])

    Article  PubMed  Google Scholar 

  • Patroniti N, Zangrillo A, Pappalardo F, Peris A, Cianchi G, Braschi A et al (2011) The Italian ECMO network experience during the 2009 influenza A (H1N1) pandemic: preparation for severe respiratory emergency outbreaks. Intensive Care Med 37(9):1447–57 (Epub 2011/07/07)

    Article  PubMed  Google Scholar 

  • Peek GJ, Mugford M, Tiruvoipati R, Wilson A, Allen E, Thalanany MM et al (2009) Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet 374(9698):1351–63 (Epub 2009/09/19])

    Article  PubMed  Google Scholar 

  • Philipp A, Muller T, Bein T, Foltan M, Schmid FX, Birnbaum D et al (2007) Inhibition of thrombocyte aggregation during extracorporeal lung assist: a case report. Perfusion 22(4):293–7 (Epub 2008/01/10)

    Article  PubMed  Google Scholar 

  • Rehder KJ, Turner DA, Cheifetz IM (2013) Extracorporeal membrane oxygenation for neonatal and pediatric respiratory failure: an evidence-based review of the past decade (2002–2012)*. Pediat Crit Care Med 14(9):851–61 (Epub 2013/10/11)

    Article  Google Scholar 

  • Schmidt M, Tachon G, Devilliers C, Muller G, Hekimian G, Brechot N et al (2013) Blood oxygenation and decarboxylation determinants during venovenous ECMO for respiratory failure in adults. Intensive Care Med 39(5):838–46 (Epub 2013/01/08])

    Article  CAS  PubMed  Google Scholar 

  • Strueber M, Hoeper MM, Fischer S, Cypel M, Warnecke G, Gottlieb J et al (2009) Bridge to thoracic organ transplantation in patients with pulmonary arterial hypertension using a pumpless lung assist device. Am J Transplant 9(4):853–7

    Article  CAS  PubMed  Google Scholar 

  • Terragni PP, Birocco A, Faggiano C, Ranieri VM (2010) Extracorporeal CO2 removal. Contrib Nephrol 165(2):185–96 (Epub 2010/04/30)

    Article  PubMed  Google Scholar 

  • Terragni P, Faggiano C, Ranieri VM (2013) Extracorporeal membrane oxygenation in adult patients with acute respiratory distress syndrome. Curr Opinion Crit Care. (Epub 2013/12/11)

    Google Scholar 

  • Webb SA, Pettila V, Seppelt I, Bellomo R, Bailey M, Cooper DJ et al (2009) Critical care services and 2009 H1N1 influenza in Australia and New Zealand. NEJM 361(20):1925–34 (Epub 2009/10/10])

    Article  PubMed  Google Scholar 

  • Wong JK, Smith TN, Pitcher HT, Hirose H, Cavarocchi NC (2012) Cerebral and lower limb near-infrared spectroscopy in adults on extracorporeal membrane oxygenation. Artif Organs 36(8):659–67 (Epub 2012/07/24])

    Article  PubMed  Google Scholar 

  • Zangrillo A, Landoni G, Biondi-Zoccai G, Greco M, Greco T, Frati G et al (2013) A meta-analysis of complications and mortality of extracorporeal membrane oxygenation. Crit Care Resusc J Australas Acad Crit Care Med 15(3):172–8 (Epub 2013/08/16])

    Google Scholar 

  • Zhou X, Loran DB, Wang D, Hyde BR, Lick SD, Zwischenberger JB (2005) Seventy-two hour gas exchange performance and hemodynamic properties of NOVALUNG iLA as a gas exchanger for arteriovenous carbon dioxide removal. Perfusion 20(6):303–8 (Epub 2005/12/21])

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Deutschland

    Dr. med. Tobias M. Bingold

  2. Thorax-, Herz-, Thorakale Gefäßchirurgie, Abteilung Kardiotechnik, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Deutschland

    Harald Keller

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  1. Dr. med. Tobias M. Bingold
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Editor information

Editors and Affiliations

  1. Klinik für Anästhesiologie, RWTH Aachen Universitätsklinikum Aachen, Aachen, Germany

    Gernot Marx

  2. Klinik für Chirurgie, Universitätsklinikum Schleswig-Holstein Campus Lübeck, Lübeck, Germany

    Elke Muhl

  3. Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Goethe-Universität Frankfurt, Frankfurt, Hessen, Germany

    Kai Zacharowski

  4. Medizinische Klinik I, Universitätsklinikum Frankfurt, Frankfurt, Germany

    Stefan Zeuzem

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Bingold, T.M., Keller, H. (2015). Unterstützung bei Lungenversagen. In: Marx, G., Muhl, E., Zacharowski, K., Zeuzem, S. (eds) Die Intensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54953-3_38

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  • DOI: https://doi.org/10.1007/978-3-642-54953-3_38

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  • Print ISBN: 978-3-642-54952-6

  • Online ISBN: 978-3-642-54953-3

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