A pheochromocytoma is a tumor of chromaffin cells, which secrete catecholamines, predominantly norepinephrine, as well as epinephrine, and rarely dopamine. The majority of pheochromocytomas are sporadic, but up to 25 % of cases are hereditary . It may be associated with multiple endocrine neoplasia syndrome, type IIA and type IIB (also known as MEN IIA and MEN IIB), von Hippel-Lindau disease, neurofibromatosis type 1 (von Recklinghausen disease), phakomatosis, and paraganglioma syndromes.
KeywordsChromaffin Cell Laparoscopic Adrenalectomy Malignant Pheochromocytoma Multiple Endocrine Neoplasia Syndrome Underlying Genetic Mutation
- 2.Mazza A, Armigliato M, Marzola MC, Schiavon L, Montemurro D, Vescovo G, Zuin M, Chondrogiannis S, Ravenni R, Opocher G, Colletti PM, Rubello D. Anti-hypertensive treatment in pheochromocytoma and paraganglioma: current management and therapeutic features. Endocrine. 2014;45:469–78.PubMedCrossRefGoogle Scholar