Skip to main content

Urosepsis

  • Chapter
  • First Online:
Book cover Urology at a Glance

Abstract

Urosepsis is defined as sepsis caused by urinary tract infection (UTI) and accounts for 25 % of all sepsis cases [1]. Patients with anatomical and/or functional abnormalities of the urinary tract and patients with comorbidities such as poor-regulated diabetes mellitus or immunosuppressive therapy are predisposed to sepsis syndrome [2]. Severe sepsis is a potentially life-threatening condition related to a mortality rate ranging between 30 and 50 % [3]. Hence, early goal-directed therapy and empirical antibiotic treatment are crucial aspects of patient care in urosepsis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Wagenlehner FME, Pilatz A, Weidner W. Urosepsis–from the view of the urologist. Int J Antimicrob Agents. 2011;38(Suppl):51–7.

    Article  PubMed  CAS  Google Scholar 

  2. Grabe M (chair), Bartoletti R, Bjerklund-Johansen TE, Çek HM, Pickard RS, Tenke P, Wagenlehner F, Wullt B. European Association of Urology 2014. Guidelines on urological infections. Sepsis syndrome in urology (Urosepsis). 2014;(5):34–8.

    Google Scholar 

  3. Satran R, Almog Y. The coagulopathy of sepsis: pathophysiology and management. Isr Med Assoc J. 2003;5(7):516–20.

    PubMed  CAS  Google Scholar 

  4. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet. 1993;341(8844):515–8.

    Article  PubMed  CAS  Google Scholar 

  5. Wagenlehner FM, Lichtenstern C, Rolfes C, Mayer K, Uhle F, Weidner W, Weigand MA. Diagnosis and management for urosepsis. Int J Urol. 2013;20(10):963–70.

    Google Scholar 

  6. Nicolle LE. Urinary tract infection. Crit Care Clin. 2013;29(3):699–715.

    Article  PubMed  Google Scholar 

  7. Li L, Parwani AV. Xanthogranulomatous pyelonephritis. Arch Pathol Lab Med. 2011;135(5):671–4.

    PubMed  Google Scholar 

  8. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20(6):86.

    Google Scholar 

  9. Glück T, Opal SM. Advances in sepsis therapy. Drugs. 2004;64(8):837–59.

    Article  PubMed  Google Scholar 

  10. Archana S, Vijaya C, Geethamani V, Savitha AK. Emphysematous pyelonephritis in a diabetic leading to renal destruction: pathological aspects of a rare case. Malays J Pathol. 2013;35(1):103–6.

    PubMed  CAS  Google Scholar 

  11. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R, Surviving Sepsis Campaign Guidelines Committee Including the Pediatric Subgroup. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med. 2013;39(2):165–228.

    Article  PubMed  CAS  Google Scholar 

  12. Yanar H, Taviloglu K, Ertekin C, Guloglu R, Zorba U, Cabioglu N, Baspinar I. Fournier’s gangrene: risk factors and strategies for management. World J Surg. 2006;30(9):1750–4.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andrea Thissen .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Heidenreich, A., Thissen, A. (2014). Urosepsis. In: Merseburger, A., Kuczyk, M., Moul, J. (eds) Urology at a Glance. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54859-8_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-54859-8_10

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54858-1

  • Online ISBN: 978-3-642-54859-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics