Structural and Functional Brain Imaging in Borderline, Antisocial, and Narcissistic Personality Disorder

  • Lars SchulzeEmail author
  • Stefan RoepkeEmail author


The aim of this chapter is to present main functional and structural brain findings from the neuroscientific study of personality disorder. In particular, this chapter will focus on borderline, antisocial, and narcissistic personality disorders. First, findings from individuals with borderline personality disorder (BPD) will be reviewed to highlight neural underpinnings of major psychopathological domains in BPD, i.e., processing and regulation of emotions, self-injurious behavior and pain processing, as well as interpersonal disturbances. Second, abnormalities of specific brain structures and functional networks of individuals with antisocial behavior and traits of psychopathy will be presented. Finally, we will discuss the few studies available from the neurobiological study of narcissistic personality disorder.


Borderline Personality Disorder Anterior Cingulate Cortex Antisocial Behavior Personality Disorder Antisocial Personality Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Anterior cingulate cortex


Blood oxygenation level dependant


Borderline personality disorder


Cavum septum pellucidum


Diffusion tensor imaging


Gray matter


Narcissistic personality disorder


Orbitofrontal cortex


Psychopathy Checklist-Revised


Positron emission tomography


Prefrontal cortex (PFC)


Psychopathic Personality Inventory


Posttraumatic stress disorder


Single-photon emission computed tomography


Voxel-based morphometry


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Copyright information

© Springer Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Clinical Psychology and PsychotherapyFreie Universität BerlinBerlinGermany
  2. 2.Department of Psychiatry and PsychotherapyCharité Universitätsmedizin BerlinBerlinGermany

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