Squamous Cell Carcinoma

  • Ryan Thorpe
  • Divya Srivastava


Squamous cell carcinoma (SCC) of the skin is more common in fair-skinned individuals but is seen in all races. Although it is less common in skin of color, it is marked by worse prognosis, with mortality rates ranging from 17 to 30 %. SCC in populations with darker skin is less likely to be related to ultraviolet radiation and more likely related to unremitting ulcers, scars, and other chronic inflammatory processes compared to populations with lighter skin. Recent surveys revealed significant false perceptions among patients that dark skin confers complete protection from skin cancer, thus signifying the need to provide better education regarding this entity in skin of color. This chapter characterizes the epidemiology, clinical features, differential diagnosis, prognosis, and treatment of SCC in skin of color.


Squamous Cell Carcinoma Actinic Keratosis Dark Skin Granular Cell Tumor Hidradenitis Suppurativa 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Bolognia JL, Jorizzo JL, Schaffer JV. Dermatology, vol 1. 3rd ed. 2012. p. 1759–93. Print.Google Scholar
  2. 2.
    Gloster HM, Neal K. Skin cancer in skin of color. J Am Acad Dermatol. 2006;55(5):741–60.PubMedCrossRefGoogle Scholar
  3. 3.
    Kelly AP, Taylor SC, editors. Dermatology for skin of color. New York: McGraw Hill; 2009. p. 291–5. Print.Google Scholar
  4. 4.
    Jackson BA. Nonmelanoma skin cancer in persons of color. Semin Cutan Med Surg. 2009;28(2):93–5.PubMedCrossRefGoogle Scholar
  5. 5.
    Bradford PT. Skin cancer in skin of color. Dermatol Nurs. 2009;21(4):170–7, 206.PubMedCentralPubMedGoogle Scholar
  6. 6.
    Battie C, Gohara M, Verschoore M, Roberts W. Skin cancer in skin of color: an update on current facts, trends, and misconceptions. J Drugs Dermatol. 2013;12(2):194–8.PubMedGoogle Scholar
  7. 7.
    Buster KJ, You Z, Fouad M, Elmets C. Skin cancer risk perceptions: a comparison across ethnicity, age, education, gender, and income. J Am Acad Dermatol. 2012;66(5):771–9.PubMedCentralPubMedCrossRefGoogle Scholar
  8. 8.
    Imahiyerobo-Ip J, Ip I, Jama S, Nadiminti U, Sanchez M. Skin cancer awareness in communities of color. J Am Acad Dermatol. 2011;64(1):198–200.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of DermatologyUniversity of Texas Southwestern Medical SchoolMansfieldUSA
  2. 2.Department of DermatologyUniversity of Texas Southwestern Medical CenterDallasUSA

Personalised recommendations