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Syphilis

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Abstract

Syphilis is a sexually transmitted infection (STI) that can be directly or congenitally acquired. The stage of the disease as well as the ethnicity, gender, and health of the patient influence the cutaneous presentation. Syphilis can mimic several dermatological conditions, especially in the secondary stage. This chapter will review the epidemiology, clinical presentation, differential diagnoses, and treatment of syphilis with an emphasis on acquired secondary-stage syphilis.

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References

  1. Ramoni S, Cusini M, Crosti C. An atlas of syphilis in a single case. Arch Dermatol. 2011;147:869–70.

    Article  PubMed  Google Scholar 

  2. LaFond R, Lukehart S. Biological basis for syphilis. Clin Microbiol Rev. 2006;19:29–49.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  3. Owsu-Edusel Jr K, et al. The association between racial disparity in income and reported sexually transmitted infections. Am J Public Health. 2012;103:910–6.

    Article  Google Scholar 

  4. Centers for Disease Control and Prevention. 2011. Sexually Transmitted Diseases Surveillance: STDs in racial and ethnic minorities. http://www.cdc.gov/std/stats11/minorities.htm. Accessed 27 July 2013.

  5. Walker J, Walker G. Congenital syphilis: a continuing but neglected problem. Semin Fetal Neonatal Med. 2007;12:198–206.

    Article  PubMed  Google Scholar 

  6. Baughn R, Musher D. Secondary syphilitic lesions. Clin Microbiol Rev. 2005;18:205–16.

    Article  PubMed Central  PubMed  Google Scholar 

  7. Mullooly C, Higgins S. Secondary syphilis: the classical triad of skin rash, mucosal ulceration, and lymphadenopathy. Int J STD AIDS. 2010;21:537–45.

    Article  CAS  PubMed  Google Scholar 

  8. Shimizu S, et al. Unusual cutaneous features of syphilis in patients positive for human immunodeficiency virus. Clin Exp Dermatol. 2009;35:169–72.

    Article  PubMed  Google Scholar 

  9. Varma R, Estcourt C, Mindel A. Syphilis, sexually transmitted diseases. 2nd ed. San Diego: Academic Press; 2013.

    Google Scholar 

  10. McMillan A, McQueen A, McLaren C. A histopathological study of secondary syphilis. J Eur Acad Dermatol Venereol. 1996;7:235–9.

    Article  Google Scholar 

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Correspondence to Arturo Ricardo Dominguez MD, BS .

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© 2014 Springer-Verlag Berlin Heidelberg

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Kinser, K., Dominguez, A.R. (2014). Syphilis. In: Jackson-Richards, D., Pandya, A. (eds) Dermatology Atlas for Skin of Color. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54446-0_36

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  • DOI: https://doi.org/10.1007/978-3-642-54446-0_36

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54445-3

  • Online ISBN: 978-3-642-54446-0

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