Abstract
Biopsy involves the removal of a tissue sample, laboratory analysis and interpretation of the results. The usual objective of biopsy has been to establish or confirm a diagnosis [1]. For example, biopsy is useful when clinical examination fails to distinguish a melanoma from a nevus or metastasis. Even when there is a confident clinical diagnosis, biopsy may be performed to determine the tumour subtype. For example, when a choroidal metastasis is diagnosed in a patient who does not have a past history of systemic malignancy, morphological and immunohistochemical examinations of the biopsy may indicate the likely site of the primary tumor so that investigations can be targeted accordingly. Increasingly, uveal melanoma biopsy is being performed to enhance prognostication, by integrating histologic and genetic findings with clinical tumor stage [2].
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Damato, B., Angi, M., Coupland, S.E., Heimann, H., Groenewald, C. (2014). Miscellaneous Uveal Biopsy Techniques. In: Damato, B., Singh, A. (eds) Clinical Ophthalmic Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54255-8_4
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DOI: https://doi.org/10.1007/978-3-642-54255-8_4
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