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Contrast-Enhanced MR Myelography

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Diseases of the Spinal Cord
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Abstract

Basically there are two different methods to perform MR myelography, with and without application of intrathecal gadolinium-based contrast agent. The myelographic effect of 3D T2w sequences was just mentioned above. The indication to apply intrathecal contrast agent is the detection of CSF leakage through the spinal dural sac in patients with spontaneous intracranial hypotension (SIH). Detection of dural leaks is important both in approving SIH and in determining the best treatment strategy. In contrast-enhanced (CE) MR myelography, hyperintense signal outside the intrathecal space in T1w sequences with spectral fat saturation (SPIR, fat sat) is usually considered as CSF leakage.

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Abbreviations

CSF:

Cerebrospinal fluid

FAT SAT:

Fat saturation

GD:

Gadolinium-based

MRI:

Contrast agent with diethylenetriaminepentacetate

SIH:

Spontaneous intracranial hypotension

SPAIR:

Spectral selection attenuated inversion recovery

SPIR:

Spectral presaturation inversion recovery

ΜRΙ:

Magnetic resonance imaging

Further Reading

  1. Akbar JJ, Luetmer PH, Schwartz KM, Hunt CH, Diehn FE, Eckel LJ (2012) The role of MR myelography with intrathecal gadolinium in localization of spinal CSF leaks in patients with spontaneous intracranial hypotension. AJNR Am J Neuroradiol 33(3):535–540

    Article  PubMed  CAS  Google Scholar 

  2. Hattingen E, DuMesnil R, Pilatus U, Raabe A, Kahles T, Beck J (2009) Contrast-enhanced MR myelography in spontaneous intracranial hypotension: description of an artefact imitating CSF leakage. Eur Radiol 19(7):1799–1808

    Article  PubMed  Google Scholar 

  3. Tali ET, Ercan N, Krumina G, Rudwan M, Mironov A, Zeng QY, Jinkins JR (2002) Intrathecal gadolinium (gadopentetate dimeglumine) enhanced magnetic resonance myelography and cisternography: results of a multicenter study. Invest Radiol 37(3):152–159

    Article  PubMed  Google Scholar 

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Correspondence to Elke Hattingen .

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Hattingen, E., Beck, J. (2015). Contrast-Enhanced MR Myelography. In: Hattingen, E., Weidauer, S., Setzer, M., Klein, J., Vrionis, F. (eds) Diseases of the Spinal Cord. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54209-1_7

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  • DOI: https://doi.org/10.1007/978-3-642-54209-1_7

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  • Publisher Name: Springer, Berlin, Heidelberg

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  • Online ISBN: 978-3-642-54209-1

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