Profiling, Isolation, Chemical Characterisation and Distribution of Gentianaceae Constituents

  • Jean-Luc Wolfender
  • Aurélie Urbain
  • Kurt Hostettmann
Chapter

Abstract

The family Gentianaceae includes about 1700 species over 90 genera. These plants are known to biosynthesise, in particular, rare polyphenolic pigments known as xanthones. They also produce flavonoids, as well as monoterpene glycosides (secoiridoids) which are their bitter principles. Numerous phytochemical studies have involved these constituents due to their pharmacological and chemotaxonomic relevance. The strategies used for the isolation of the different constituents of the Gentianaceae as well as their chemical characterisation are discussed, and different analytical methods (LC-MS, LC-UV-PDA and LC-NMR) used for the profiling of these constituents in different species of the Gentianaceae are presented. Examples are also given how these approaches are used to establish chemotaxonomic relationships between species with discussion on chemotaxonomic aspects mainly focused on two subtribes, the Gentianinae and Swertiinae.

Keywords

High Performance Liquid Chromatography Xylose Glycoside Saponin Glucoside 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Jean-Luc Wolfender
    • 1
  • Aurélie Urbain
    • 2
  • Kurt Hostettmann
    • 1
  1. 1.School of Pharmaceutical SciencesUniversity of Geneva, University of LausanneGeneva 4Switzerland
  2. 2.Faculty of PharmacyUniversity of StrasbourgIllkirchFrance

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