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Abstract

The application of marine resources for the formulation of cosmetics has been known for centuries. Marine organisms produce unique compounds, which are not found in terrestrial sources, to provide protection against hard environmental conditions. They have been used both to confer:

  • Physicochemical functional properties to the cosmetic product, such as texture, emulsifying properties or color,

  • Bioactive properties, including remineralizing, emollient, hydrating, antioxidant, sunscreening among others.

In this chapter, the major functional and biological activities of components isolated from marines sources, including micro and macroorganisms and with special emphasis on algae, are reviewed in relation to their application to cosmetics. Both the traditionally used compounds and fractions and those isolated and characterized in recent years are presented.

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Abbreviations

HSV :

herpes simplex virus

12-DS:

12-doxylstearic acid

AAPH:

2,2 -azobis(2-amidino-propane) dihydrochloride

ABAP:

2,2 -azo-bis-2-amidinopropane

ABTS:

2,2 -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)

ADBAC:

alkyldimethylbenzylammonium chloride

AHA:

α-hydroxy acids

BHT:

butylated hydroxytoluene

DHA:

docosahexaenoic acid

DPPH:

2,2-diphenyl-1-picrylhydrazyl

EDTA:

ethylenediaminetetraacetic acid

EPA:

eicosapentaenoic acid

FD&C:

Food, Drug, and Cosmetic Act

FDA:

Food and Drug Administration

FP&LA:

Fair Packaging and Labeling Act

FcεRI:

Fc region of immunoglobulin E

HSV:

herpes simplex virus

IL:

interleukin

INCI:

International Nomenclature of Cosmetic Ingredients

IgE:

immunoglobulin E

MAA:

mycosporine-like amino acid

MEL-28:

human melanoma cell

NB-L:

nitrobenzene with linoleic acid

NCI:

National Cancer Institute

OTC:

over-the-counter

PUFA:

polyunsaturated fatty acid

ROS:

reactive oxygen species

SOD:

superoxide dismutase

SP:

sulfated polysaccharide

TRAP:

total radical antioxidant parameter

Th2:

T helper 2 cells

UVB:

ultraviolet B radiation

UV:

ultraviolet

l-DOPA:

l-3,4-dihydroxyphenylalanine

mRNA:

messenger RNA

References

  1. M.T. Alcalde-Pérez: Activos cosméticos de origen marino: Algas, macromoléculas y otros componentes, OFFARM 23, 100–104 (2004)

    Google Scholar 

  2. M.T. Alcalde-Pérez: Cosmética natural y ecológica: Regulación y clasificación, OFFARM 27, 96–104 (2008)

    Google Scholar 

  3. A. Kijjoa, P. Sawangwong: Drugs and cosmetics from the sea, Mar. Drugs 2, 73–82 (2004)

    Article  CAS  Google Scholar 

  4. S. Saraf, C. Kaur: Phytoconstituents as photoprotective novel cosmetic formulations, Pharmacogn. Rev. 4, 1–11 (2010)

    Article  CAS  Google Scholar 

  5. D.J. De Vries, P.M. Beart: Fishing for drugs from the sea: Status and strategies, Trends Pharmacol. Sci. 16, 275–279 (1995)

    Article  Google Scholar 

  6. A. Aneiros, A. Garateix: Bioactive peptides from marine sources: Pharmacological properties and isolation procedures, J. Chromatogr. B 803, 41–53 (2004)

    Article  CAS  Google Scholar 

  7. D. Leary, M. Vierros, G. Hamon, S. Arico, C. Monagle: Marine genetic resources: A review of scientific and commercial interest, Mar. Policy 33, 183–194 (2009)

    Article  Google Scholar 

  8. J. Querellou, T. Børresen, C. Boyen, A. Dobson, M. Höfle, A. Ianora, M. Jaspars, A. Kijjoa, J. Olafsen, G. Rigos, R. Wijffels: A new vision and strategy for Europe (Marine Board-ESF Position Paper), Mar. Biotechnol. 15, 50–52 (2010)

    Google Scholar 

  9. J.F. Imhoff, A. Labes, J. Wiese: Bio-mining the microbial treasures of the ocean: New natural products, Biotechnol. Adv. 29, 468–482 (2011)

    Article  CAS  Google Scholar 

  10. P. Spolaore, C. Joannis-Cassan, E. Duran, A. Isambert: Commercial applications of microalgae, J. Biosci. Bioeng. 101, 87–96 (2006)

    Article  CAS  Google Scholar 

  11. J.H. Fitton, M. Irhimeh, N. Falk: Macroalgal fucoidan extracts: A new oportunity for marine cosmetics, Cosmet. Toilet. 122, 55–64 (2007)

    CAS  Google Scholar 

  12. S.K. Kim, Y.D. Ravichandran, S.B. Khan, Y.T. Kim: Prospective of the cosmeceuticals derived from marine organisms, Biotechnol. Bioprocess E 13, 511–523 (2008)

    Article  CAS  Google Scholar 

  13. F.S. Brandt, A. Cazzaniga, M. Hann: Cosmeceuticals: Current trends and market analysis, Sem. Cutan. Med. Surg. 30, 141–143 (2011)

    Article  CAS  Google Scholar 

  14. S.R. Milstein, J.E. Bailey, A.R. Halper: Definition of cosmetics. In: Handbook of Cosmetic Science and Technology, ed. by A.O. Barel, M. Paye, H.I. Maibach (Marcel Dekker, New York 2005) pp. 5–18

    Google Scholar 

  15. R.C. Lindenschmidt, F.B. Anastasia, M. Dorta, L. Bansil: Global cosmetic regulatory harmonization, Toxicology 160, 237–241 (2001)

    Article  CAS  Google Scholar 

  16. G.J. Nohynek, E. Antignac, T. Re, H. Toutain: Safety assessment of personal care products/cosmetics and their ingredients, Toxicol. Appl. Pharmacol. 243, 239–259 (2010)

    Article  CAS  Google Scholar 

  17. J. Vernon, T.A. Nwaogu: Comparative Study on Cosmetics Legislation in the EU and Other Principal Markets with Special Attention to so-called Borderline Products, prepared for European Commission, DG Enterprise (RPA, Loddon 2004) pp. 13–43

    Google Scholar 

  18. G. Pisacane: Cosmetics market regulation in Asian countries, Househ. Pers. Care Today 4, 21–25 (2009)

    Google Scholar 

  19. T. Srikanth, S.S. Hussen, A. Abha, S.G. Vasantharaju, S. Gummudavelly: A comparative view on cosmetic regulations: USA, EU and INDIA, Der Pharm. Lett. 3, 334–341 (2011)

    Google Scholar 

  20. EC: Regulation (EC) No. 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products

    Google Scholar 

  21. Council Directive 76/768/EEC of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products

    Google Scholar 

  22. S.K. Kim (Ed.): Marine Cosmeceuticals. Trends and Prospects (CRC, Boca Raton 2011)

    Google Scholar 

  23. D. Kligman: Cosmeceuticals, Dermatol. Clin. 18, 609–615 (2000)

    Article  CAS  Google Scholar 

  24. K. $\text{\={O}}$ba: Drugs versus cosmetics: Cosmeceuticals? In: Cosmeceuticals. Drugs vs. Cosmetics, ed. by P. Elsner, H.I. Maibach (Marcel Dekker, Basel 2000) pp. 251–258

    Google Scholar 

  25. B.J. Vermeer: Definition. In: Cosmeceuticals. Drugs Vs. Cosmetics, ed. by P. Elsner, H.I. Maibach (Marcel Dekker, Basel 2000) pp. 22–25

    Google Scholar 

  26. C.M. Choi, D.S. Berson: Cosmeceuticals, Semin. Cutan. Med. Surg. 25, 163–168 (2006)

    Article  CAS  Google Scholar 

  27. M. Amer, M. Maged: Cosmeceuticals versus pharmaceuticals, Clin. Dermatol. 27, 428–430 (2009)

    Article  Google Scholar 

  28. D.B. Newgreen: Review of the regulation of products at the interface between cosmetics and therapeutic goods (Report prepared for the TGA), Review 1, 23–85 (2005)

    Google Scholar 

  29. E.C. Gendler, C. Rizzo: Cosmeceuticals and the practice of Dermatology. In: Cosmeceuticals, 2nd edn., Procedures in Cosmetic Dermatology, ed. by Z.D. Draelos, M. Alan (Suanders Elsevier, Amsterdam 2010) pp. 31–43

    Google Scholar 

  30. P.M. Hyman, R. Carvajal: Drugs and other product choices, Dermatol. Ther. 22, 216–224 (2009)

    Article  Google Scholar 

  31. K.W. Gellenbeck: Utilization of algal materials for nutraceutical and cosmeceutical applications-what do manufacturers need to know?, J. Appl. Phycol. 24, 309–313 (2012)

    Article  Google Scholar 

  32. L. Verschooten, S. Claerhout, A. Van Laethem, P. Agostinis, M. Garmyn: New strategies of photoprotection, Photochem. Photobiol. 82, 1016–1023 (2006)

    Article  CAS  Google Scholar 

  33. V.K. Dhargalkar, X.N. Verlecar: Southern Ocean seaweeds: A resource for exploration in food and drugs, Aquaculture 287, 229–242 (2009)

    Article  CAS  Google Scholar 

  34. S. Tosi, N. Kostadinova, E. Krumova, S. Pashova, V. Dishliiska, B. Spassova, S. Vassilev, M. Angelova: Antioxidant enzyme activity of filamentous fungi isolated from Livingston Island, maritime Antarctica, Polar Biol. 33, 1227–1237 (2010)

    Article  Google Scholar 

  35. M. Zubia, D. Robledo, Y. Freile-Pelegrin: Antioxidant activities in tropical marine macroalgae from the Yucatan Peninsula, Mexico, J. Appl. Phycol. 19, 449–458 (2007)

    Article  Google Scholar 

  36. T.H. Kabri, E. Arab-Tehrany, N. Belhaj, M. Linder: Physico-chemical characterization of nano-emulsions in cosmetic matrix enriched on omega-3, J. Nanobiotechnol. 9, 1–8 (2011)

    Article  CAS  Google Scholar 

  37. E. Proksch, J.M. Brandner, J.M. Jensen: The skin: An indispensable barrier, Exp. Dermatol. 17, 1063–1072 (2008)

    Article  Google Scholar 

  38. G.J. Fisher, S. Kang, J. Varani, Z. Bata-Csorgo, Y. Wan, S. Datta, J.J. Voorhees: Mechanisms of photoaging and chronological skin aging, Arch. Dermatol. 138, 1462–1470 (2002)

    Article  CAS  Google Scholar 

  39. M.A. Farage, K.W. Miller, P. Elsner, H.I. Maibach: Intrinsic and extrinsic factors in skin aging: A review, Int. J. Cosmet. Sci. 30, 87–95 (2008)

    Article  CAS  Google Scholar 

  40. A.W. Johnson: Cosmeceuticals: Functions and the skin barrier. In: Cosmeceuticals, 2nd edn., Procedures in Cosmetic Dermatology, ed. by Z.D. Draelos, M. Alan (Elsevier, Amsterdam 2010) pp. 43–57

    Google Scholar 

  41. S. Pillai, M. Cornell, C. Oresajo: Epidermal barrier. In: Cosmetic Dermatology: Products and Procedures, ed. by Z.D. Draelos (Wiley-Blackwell, Oxford 2010) pp. 3–12

    Google Scholar 

  42. M. Cornell, S. Pillai, C. Oresajo: Percutaneous delivery of cosmetic actives to the skin. In: Cosmetic Dermatology: Products and Procedures, ed. by Z.D. Draelos (Wiley-Blackwell, Oxford 2010) pp. 62–70

    Chapter  Google Scholar 

  43. N. Golubovic-Liakopoulos, S.R. Simon, B. Shah: Nanotechnology use with cosmeceuticals, Semin. Cutan. Med. Surg. 30, 176–180 (2011)

    Article  CAS  Google Scholar 

  44. J.D. Desai, I.M. Banat: Microbial production of surfactants and their commercial potential, Microbiol. Mol. Biol. Rev. 61, 47–64 (1997)

    CAS  Google Scholar 

  45. S.K. Satpute, I.M. Banat, P.K. Dhakephalkar, A.G. Banpurkar, B.A. Chopade: Biosurfactans, bioemulsifiers and exopolysaccharides from marine microorganisms, Biotechnol. Adv. 28, 436–450 (2010)

    Article  CAS  Google Scholar 

  46. S. Navon-Venezia, Z. Zosim, A. Gottlieb, R. Legmann, S. Carmeli, E.Z. Ron, E. Rosenberg: Alasan, a new bioemulsifier from Acinetobacter radioresistens, Appl. Environ. Microbiol. 61, 3240–3244 (1995)

    CAS  Google Scholar 

  47. D.R. Husain, M. Goutx, M. Acquaviva, M. Gilewicz, J.C. Bertrand: The effect of temperature on eicosane substrate uptake modes by a marine bacterium Pseudomonas nautica strain 617: relationship with the biochemical content of cells and supernatants, World J. Microbiol. Biotechnol. 13, 587–590 (1997)

    Article  CAS  Google Scholar 

  48. S. Maneerat, K. Phetrong: Isolation of biosurfactant-producing marine bacteria and characteristics of selected biosurfactant, Songklanakarin, J. Sci. Technol. 29, 781–791 (2007)

    Google Scholar 

  49. C.R. Kokare, S.S. Kadam, K.R. Mahadik, B.A. Chopade: Studies on bioemulsifier production from marine Streptomyces sp. S1, Indian J. Biotechnol. 6, 78–84 (2007)

    CAS  Google Scholar 

  50. P.F.F. Amaral, J.M. da Silva, M. Lehocky, A.M.V. Barros-Timmons, M.A.Z. Coelho, I.M. Marrucho, J.A.P. Coutinho: Production and characterization of a bioemulsifier from Yarrowia lipolytica, Process Biochem. 41, 1894–1898 (2006)

    Article  CAS  Google Scholar 

  51. J.K. Oloke, B.R. Glick: Production of bioemulsifier by an unusual isolate of salmon/red melanin containing Rhodotorula glutinis, Afr. J. Biotechnol. 4, 164–171 (2005)

    CAS  Google Scholar 

  52. T. Gutiérrez, B. Mulloy, K. Black, D.H. Green: Glycoprotein emulsifiers from two marine Halomonas species: Chemical and physical characterization, J. Appl. Microbiol. 103, 1716–1727 (2007)

    Article  CAS  Google Scholar 

  53. M. Pepi, A. Cesaro, G. Liut, F. Baldi: An Antarctic psychrotrophic bacterium Halomonas sp. ANT-3b, growing on n-hexadecane, produces a new emulsifying glycolipid, FEMS Microbiol. Ecol. 53, 157–166 (2005)

    Article  CAS  Google Scholar 

  54. F. Peng, Z. Liu, L. Wang, Z. Shao: An oil-degrading bacterium: Rhodococcus erythropolis strain 3C-9 and its biosurfactants, J. Appl. Microbiol. 102, 1603–1611 (2007)

    Article  CAS  Google Scholar 

  55. W.R. Abraham, H. Meyer, M. Yakimov: Novel glycine containing glucolipids from the alkane using bacterium Alcanivorax borkumensis, Biochem. Biophys. Acta 1393, 57–62 (1998)

    Article  CAS  Google Scholar 

  56. P. Das, S. Mukherjee, R. Sen: Antimicrobial potential of a lipopeptide biosurfactant derived from a marine Bacillus circulans, J. Appl. Microbiol. 104, 1675–1684 (2008)

    Article  CAS  Google Scholar 

  57. S. Mukherjee, P. Das, C. Sivapathasekaran, R. Sen: Antimicrobial biosurfactants from marine Bacillus circulans: Extracellular synthesis and purification, Lett. Appl. Microbiol. 48, 281–288 (2009)

    Article  CAS  Google Scholar 

  58. R. Gandhimathi, G. Seghal Kiran, T.A. Hema, J. Selvin, T. Rajeetha Raviji, S. Shanmughapriya: Production and characterization of lipopeptide biosurfactant by a sponge-associated marine actinomycetes Nocardiopsis alba MSA10, Bioprocess Biosyst. Eng. 32, 825–835 (2009)

    Article  CAS  Google Scholar 

  59. A. Khopade, B. Ren, X.Y. Liu, K. Mahadik, L. Zhang, C. Kokare: Production and characterization of biosurfactant from marine Streptomyces species B3, J. Colloid Interface Sci. 367, 311–318 (2012)

    Article  CAS  Google Scholar 

  60. S. Maneerat, T. Nitoda, H. Kanzaki, F. Kawai: Bile acids are new products of a marine bacterium, Myroides sp. strain SM1, Appl. Microbiol. Biotechnol. 67, 679–683 (2005)

    Article  CAS  Google Scholar 

  61. T.L. Maugeri, C. Gugliandolo, D. Caccamo, A. Panico, L. Lama, A. Gambacorta, B. Nicolaus: Halophilic thermotolerant Bacillus isolated from a marine hot spring able to produce a new exopolysaccharide, Biotechnol. Lett. 24, 515–519 (2002)

    Article  CAS  Google Scholar 

  62. A.S. Kumar, K. Mody, B. Jha: Evaluation of biosurfactant/bioemulsifier production by a marine bacterium, Bull. Environ. Contam. Toxicol. 79, 617–621 (2007)

    Article  CAS  Google Scholar 

  63. Z. Chi, C.D. Su, W.D. Lu: A new exopolysaccharide produced by marine Cyanothece sp. 113, Bioresour. Technol. 98, 1329–1332 (2007)

    Article  CAS  Google Scholar 

  64. S. Raut, S.S. Bhadoriya, V. Uplanchiwar, V. Mishra, A. Gahane, S.K. Jain: Lecithin organogel: A unique micellar system for the delivery of bioactive agents in the treatment of skin aging, Acta Pharm. Sinica B 2, 8–15 (2012)

    Article  CAS  Google Scholar 

  65. V.L. Campo, D.F. Kawano, D. da Braz Silva, I. Carvalho: Carrageenans: Biological properties, chemical modifications and structural analysis – A review, Carbohydr. Polym. 77, 167–180 (2009)

    Article  CAS  Google Scholar 

  66. R.H. Charlier, M.C.P. Chaineux: The healing sea: A sustainable coastal ocean resource: Thalassotherapy, J. Coast. Res. 25, 838–856 (2009)

    Article  Google Scholar 

  67. M. Rinaudo, Chitin, chitosan: Properties and applications, Prog. Polym. Sci. 31, 603–632 (2006)

    Article  CAS  Google Scholar 

  68. N.K. Mathur, C.K. Narang: Chitin and chitosan, versatile polysaccharides from marine animals, J. Chem. Educ. 67, 938–942 (1990)

    Article  CAS  Google Scholar 

  69. M.C. Gómez-Guillén, B. Giménez, M.E. López-Caballero, M.P. Montero: Functional and bioactive properties of collagen and gelatin from alternative sources, A review, Food Hydrocoll. 25, 1813–1827 (2011)

    Article  CAS  Google Scholar 

  70. P. Sivakumar, L. Suguna, G. Chandrakasan: Molecular species of collagen in the intramuscular connective tissues of the marine crab, Scylla serrata, Comp. Biochem. Physiol. B Biochem. Mol. Biol. 125, 555–562 (2000)

    Article  CAS  Google Scholar 

  71. T. Nagai, N. Suzuki: Partial characterization of collagen from purple sea urchin (Anthocidaris crassispina) test, Int. J. Food Sci. Technol. 35, 497–501 (2000)

    Article  CAS  Google Scholar 

  72. D. Swatschek, W. Schatton, W.E.G. Müller, J. Kreuter: Microparticles derived from marine sponge collagen (SCMPs): Preparation, characterization and suitability for dermal delivery of all-trans retinol, Eur. J. Pharm. Biopharm. 54, 125–133 (2002)

    Article  CAS  Google Scholar 

  73. S. Mizuta, T. Miyagi, T. Nishimiya, R. Yoshinaka: Partial characterization of collagen in several bivalve molluscs, Food Chem. 87, 83–88 (2004)

    Article  CAS  Google Scholar 

  74. R. Pallela, S. Bojja, V.R. Janapala: Biochemical and biophysical characterization of collagens of marine sponge, Ircinia fusca (Porifera: Demospongiae: Irciniidae), Int. J. Biol. Macromol. 49, 85–92 (2011)

    Article  CAS  Google Scholar 

  75. M.C. Gómez-Guillén, J. Turnay, M.D. Fernández-Díaz, N. Ulmo, M.A. Lizarbe, P. Montero: Structural and physical properties of gelatin extracted from different marine species: A comparative study, Food Hydrocoll. 16, 25–34 (2002)

    Article  Google Scholar 

  76. A.A. Karim, R. Bhat: Fish gelatin: Properties, challenges, and prospects as an alternative to mammalian gelatins, Food Hydrocoll. 23, 563–576 (2009)

    Article  CAS  Google Scholar 

  77. K. Miyagawa, C.I. Yamamotoyoichi: Production of phycocyanin-containing blue pigment from blue-green alga and cosmetic containing said pigment, JP Patent 123865 (1989)

    Google Scholar 

  78. R. Bermejo Román, J.M. Alvárez-Pez, F.G. Acién Fernández, E. Molina Grima: Recovery of pure B-phycoerythrin from the microalga Porphyridium cruentum, J. Biotechnol. 93(1), 73–85 (2002)

    Article  Google Scholar 

  79. R. Rossano, N. Ungaro, A. D'Ambrosio, G.M. Liuzzi, P. Riccio: Extracting and purifying R-phycoerythrin from Mediterranean red algae Corallina elongata Ellis & Solander, J. Biotechnol. 101, 289–293 (2003)

    Article  CAS  Google Scholar 

  80. A. Khanafari, A. Saberi, M. Azar, G. Vossoghi, S. Jamili, B. Sabbaghzadeh, B. : Extraction of astaxanthin esters from shrimp waste by chemical and microbial methods, Iran. J. Environ. Health Sci. Eng. 4(2), 93–98 (2007)

    CAS  Google Scholar 

  81. T.S. Trung, P.T.D. Phuong: Bioactive compounds from by-products of shrimp processing industry in Vietnam, J. Food Drug Anal. 20, 194–197 (2012)

    CAS  Google Scholar 

  82. J. Synowiecki, N.A. Al-Khateeb: Production, properties, and some new applications of chitin and its derivatives, Crit. Rev. Food Sci. Nutr. 43, 145–171 (2003)

    Article  CAS  Google Scholar 

  83. K. Kurita: Chitin and chitosan: Functional biopolymers from marine crustaceans, Mar. Biotechnol. 8, 203–226 (2006)

    Article  CAS  Google Scholar 

  84. Z. Degim, N. Celebi, H. Sayan, A. Babül, D. Erdoğan, G. Take: An investigation on skin wound healing in mice with a taurine-chitosan gel formulation, Amino Acids 22, 187–198 (2002)

    Article  CAS  Google Scholar 

  85. T. Nagai, Y. Araki, N. Suzuki: Collagen of the skin of ocellate puffer fish (Takifugu rubripes), Food Chem. 78, 173–177 (2002)

    Article  CAS  Google Scholar 

  86. N. Domoto, T. Koriyama, B.S. Chu, T. Tsuji: Evaluation of the efficacy of orange roughy (Hoplostetbus atlanticus) oil in subjects with dry skin, Int. J. Cosmet. Sci. 34, 322–327 (2012)

    Article  CAS  Google Scholar 

  87. S. Sekar, M. Chandramohan: Phycobiliproteins as a commodity: Trends in applied research, patents and commercialization, J. Appl. Phycol. 20, 113–136 (2008)

    Article  Google Scholar 

  88. S. Arad, A. Yaron: Natural pigments from red microalgae for use in foods and cosmetics, Trends Food Sci. Technol. 3, 92–97 (1992)

    Article  CAS  Google Scholar 

  89. R. Bermejo, J.M. Álvarez-Pez, F.G. Acién, E. Molina: Recovery of pure B-phycoerythrin from the microalga Porphyridium cruentum, J. Biotechnol. 93, 73–85 (2002)

    Article  Google Scholar 

  90. R. Bermejo, E.M. Talavera, C. del Valle, J.M. Álvarez-Pez: C-phycocyanin incorporated into reverse micelles: A fluorescence study, Colloids Surf. B 18, 51–59 (2000)

    Article  CAS  Google Scholar 

  91. P.J. Viskari, C.L. Colyer: Rapid extraction of phycobiliproteins from cultures cyanobacteria samples, Anal. Biochem. 319, 263–271 (2003)

    Article  CAS  Google Scholar 

  92. Jaswir, D. Noviendri, R.F. Hasrini, F. Octavianti: Carotenoids: Sources, medicinal properties and their application in food and nutraceutical industry, J. Med. Plants Res. 5, 7119–7131 (2011)

    CAS  Google Scholar 

  93. E. Christaki, E. Bonos, I. Giannenas, P. Florou-Paneri: Functional properties of carotenoids originating from algae, J. Sci. Food Agric. 93, 5–11 (2013)

    Article  CAS  Google Scholar 

  94. D.H. Ngo, T.S. Vo, D.N. Ngo, I. Wijesekara, S.K. Kim: Biological activities and potential health benefits of bioactive peptides derived from marine organisms, Int. J. Biol. Macromol. 51, 378–383 (2012)

    Article  CAS  Google Scholar 

  95. J. Peng, J.P. Yuan, C.F. Wu, J.H. Wang: Fucoxanthin, a marine carotenoid present in brown seaweeds and diatoms: Metabolism and bioactivities relevant to human health, Mar. Drugs 9, 1806–1828 (2011)

    Article  CAS  Google Scholar 

  96. G. Riccioni, L. Speranza, M. Pesce, S. Cusenza, N. D'Orazio, M.J. Glade: Novel phytonutrient contributors to antioxidant protection against cardiovascular disease, Nutrition 28, 605–610 (2012)

    Article  CAS  Google Scholar 

  97. H. Maeda, M. Hosokawa, T. Sashima, K. Miyashita: Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice, J. Agric. Food Chem. 55, 7701–7706 (2007)

    Article  CAS  Google Scholar 

  98. H. Maeda, M. Hosokawa, T. Sashima, K. Murakami-Funayama, K. Miyashita: Anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model, Mol. Med. Rep. 2, 897–902 (2009)

    Article  CAS  Google Scholar 

  99. K. Miyashita, H. Maeda, T. Tsukui, T. Okada, M. Hosokawa: Anti-obesity effect of allene carotenoids, fucoxanthin and neoxanthin from seaweeds and vegetables, Acta Hortic. 841, 167–171 (2009)

    Article  CAS  Google Scholar 

  100. A.E. Batista González, M.B. Charles, J. Mancini-Filho, A. Vidal Novoa: Seaweeds as sources of antioxidant phytomedicines, Rev. Cubana Plant. Med. 14, 1–18 (2009)

    Google Scholar 

  101. S.N. Sunassee, M.T. Davies-Coleman: Cytotoxic and antioxidant marine prenylated quinones and hydroquinones, Nat. Prod. Rep. 29, 513–535 (2012)

    Article  CAS  Google Scholar 

  102. E.M. Balboa, E. Conde, A. Moure, E. Falque, H. Dominguez: In vitro antioxidant properties of crude extracts and compounds from brown algae, Food Chem. 138, 1764–1785 (2013)

    Article  CAS  Google Scholar 

  103. S. Ren, J. Li, H. Guan: The antioxidant effects of complexes of tilapia fish skin collagen and different marine oligosaccharides, J. Ocean Univ. China 9, 399–407 (2010)

    Article  CAS  Google Scholar 

  104. M. Foti, M. Piattelli, V. Amico, G. Ruberto: Antioxidant activity of phenolic meroditerpenoids from marine algae, J. Photochem. Photobiol. B: Biol. 26, 159–164 (1994)

    Article  CAS  Google Scholar 

  105. Y.X. Li, S.K. Kim: Utilization of seaweed derived ingredients as potential antioxidants and functional ingredients in the food industry: An overview, Food Sci. Biotechnol. 20, 1464–1466 (2011)

    Google Scholar 

  106. A.P. Rivera, M.M. Uy: In vitro antioxidant and cytotoxic activities of some marine sponges collected off Misamis Oriental coast, Philippines, E-J. Chem. 9, 354–358 (2012)

    Article  CAS  Google Scholar 

  107. J.T. Ryan, R.P. Ross, D. Bolton, G.F. Fitzgerald, C. Stanton: Bioactive peptides from muscle sources: Meat and fish, Nutrients 3, 765–791 (2011)

    Article  CAS  Google Scholar 

  108. M. Chalamaiah, B. Dinesh Kumar, R. Hemalatha, T. Jyothirmayi: Fish protein hydrolysates: Proximate composition, amino acid composition, antioxidant activities and applications: A review, Food Chem. 35, 3020–3038 (2012)

    Article  CAS  Google Scholar 

  109. P.A. Harnedy, R.J. FitzGerald: Bioactive proteins, peptides and amino acids from macroalgae, J. Phycol. 47, 218–232 (2011)

    Article  CAS  Google Scholar 

  110. L. Najafian, A.S. Babji: A review of fish-derived antioxidant and antimicrobial peptides: Their production, assessment, and applications, Peptides 33, 178–185 (2012)

    Article  CAS  Google Scholar 

  111. S.H. Eom, Y.M. Kim, S.K. Kim: Antimicrobial effect of phlorotannins from marine brown algae, Food Chem. Toxicol. 50, 3251–3255 (2012)

    Article  CAS  Google Scholar 

  112. N.V. Thomas, S.K. Kim: Potential pharmacological applications of polyphenolic derivatives from marine brown algae, Environ. Toxicol. Pharmacol. 32, 325–335 (2011)

    Article  CAS  Google Scholar 

  113. B. Queguineur, L. Goya, S. Ramos, M.A. Martín, R. Mateos, M.D. Guiry, L. Bravo: Effect of phlorotannin-rich extracts of Ascophyllum nodosum and Himanthalia elongata (Phaeophyceae) on cellular oxidative markers in human HepG2 cells, J. Appl. Phycol. 25, 1–11 (2013)

    Article  CAS  Google Scholar 

  114. K. Murat, O. Ilkay, A.A. Mahmud, F.S. Şenol, A. Tahir, S. Bilge: Antioxidant and anticholinesterase assets and liquid chromatography-mass spectrometry preface of various fresh-water and marine macroalgae, Pharmacogn. Mag. 5, 291–297 (2009)

    Article  Google Scholar 

  115. A. Fujisawa, W.C. Dunlap, Y. Yamamoto: Vitamin E protection in the biochemical adaptation of marine organisms to cold-water environments, Comp. Biochem. Physiol. Part B: Biochem. Mol. Biol. 157, 145–158 (2010)

    Article  CAS  Google Scholar 

  116. C. Xue, G. Yu, T. Hirata, J. Terao, H. Lin: Antioxidative activities of several marine polysaccharides evaluated in a phosphatidylcholine-liposomal suspension and organic solvents, Biosci. Biotechnol. Biochem. 62, 206–209 (1998)

    Article  CAS  Google Scholar 

  117. J. Wang, X. Jiang, H. Mou: Anti-oxidation of agar oligosaccharides produced by agarase from a marine bacterium, J. Appl. Phycol. 16, 333–340 (2004)

    Article  CAS  Google Scholar 

  118. H. Yin, Y. Du, J. Zhang: Low molecular weight and oligomeric chitosans and their bioactivities, Curr. Top. Med. Chem. 9, 1546–1559 (2009)

    Article  CAS  Google Scholar 

  119. L. Hayashi, R.P. Reis: Cultivation of the red algae Kappaphycus alvarezii in Brazil and its pharmacological potential, Rev. Bras. Farmacogn. 22, 748–752 (2012)

    Article  CAS  Google Scholar 

  120. X. Zhao, B. Li, C. Xue, L. Sun: Effect of molecular weight on the antioxidant property of low molecular weight alginate from Laminaria japonica, J. Appl. Phycol. 24, 295–300 (2012)

    Article  CAS  Google Scholar 

  121. V.K. Morya, J. Kim, E.K. Kim: Algal fucoidan: Structural and size-dependent bioactivities and their perspectives, Appl. Microbiol. Biotechnol. 93, 71–82 (2012)

    Article  CAS  Google Scholar 

  122. A.M. O'Sullivan, Y.C. O'Callaghan, M.N. O'Grady, B. Queguineur, D. Hanniffy, D.J. Troy, J.P. Kerry, N.-M. O'Brien: In vitro and cellular antioxidant activities of seaweeds extracts prepared from five seaweeds harvested in spring from the west coast of Ireland, Food Chem. 126, 1064–1070 (2011)

    Article  CAS  Google Scholar 

  123. Y. Li, Z.J. Qian, B. Ryu, S.H. Lee, M.M. Kim, S.K. Kim: Chemical components and its antioxidant properties in vitro: An edible marine brown alga, Ecklonia cava, Bioorg. Med. Chem. 17, 1963–1973 (2009)

    Article  CAS  Google Scholar 

  124. Y. Zou, Z.J. Qian, Y. Li, M.M. Kim, S.H. Lee, S.K. Kim: Antioxidant effects of phlorotannins isolated from Ishige okamurae in free radical mediated oxidative systems, J. Agric. Food Chem. 56, 7001–7009 (2008)

    Article  CAS  Google Scholar 

  125. A.R. Kim, T.S. Shin, M.S. Lee, J.Y. Park, K.E. Park, N.Y. Yoon, N.Y. , J.S. Kim, J.S. Choi, B.C. Jang, D.S. Byun, N.K. Park, H.R. Kim: Isolation and identification of phlorotannins from Ecklonia stolonifera with antioxidant and anti-inflammatory properties, J. Agric. Food Chem. 57, 3483–3489 (2009)

    Article  CAS  Google Scholar 

  126. S.J. Heo, S.C. Ko, S.M. Kang, S.H. Cha, S.H. Lee, D.H. Kang, W.K. Jung, A. Affan, C. Oh, Y.J. Jeon: Inhibitory effect of diphlorethohydroxycarmalol on melanogenesis and its protective effect against UV-B radiation-induced cell damage, Food Chem. Toxicol. 48, 1355–1361 (2010)

    Article  CAS  Google Scholar 

  127. W.A.J.P. Wijesinghe, Y.J. Jeon: Biological activities and potential cosmeceutical applications of bioactive components from brown seaweeds: A review, Phytochem. Rev. 10, 431–443 (2011)

    Article  CAS  Google Scholar 

  128. A. Alemán, B. Giménez, P. Montero, M.C. Gómez-Guillén: Antioxidant activity of several marine skin gelatins, LWT – Food Sci. Technol. 44, 407–413 (2011)

    Article  CAS  Google Scholar 

  129. G.M. Suárez-Jiménez, A. Burgos-Hernández, J.M. Ezquerra-Brauer: Bioactive peptides and depsipeptides with anticancer potential: Sources from marine animals, Mar. Drugs 10, 963–986 (2012)

    Article  CAS  Google Scholar 

  130. E.M. Arbeloa, C.L. Ramírez, R.A. Procaccini, M.S. Churio: Electrochemical characterization of the marine antioxidant gadusol, Nat. Prod. Commun. 7, 1211–1214 (2012)

    CAS  Google Scholar 

  131. K.L. González García, O. Valdés Iglesias, A. Laguna, M. Díaz Martínez, J.A. González Lavaut: Efecto antioxidante y contenido polifenólico de Syringodium filiforme (Cymodoceaceae), Rev. Biol. Trop. 59, 465–472 (2011)

    Google Scholar 

  132. Y.X. Li, Y. Li, Z.J. Qian, M.M. Kim, S.K. Kim: In vitro antioxidant activity of 5-HMF isolated from marine red alga Laurencia undulata in free-radical-mediated oxidative systems, J. Microbiol. Biotechnol. 19, 1319–1327 (2009)

    CAS  Google Scholar 

  133. S.J. Heo, S.C. Ko, S.H. Cha, D.H. Kang, H.S. Park, Y.U. Choi, D. Kim, W.K. Jung, Y.J. Jeon: Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation, Toxicol. In Vitro 23, 1123–1130 (2009)

    Article  CAS  Google Scholar 

  134. F. de la Coba, J. Aguilera, M.V. de Galves, M. Alvarez, F.L. Figueroa, E. Herrera: Prevention of ultraviolet effects on clinical and histopathological changes, as well as the heat shock protein-70 expression in mouse skin by topical application of algal UV-absorbing compounds, J. Dermatol. Sci. 55, 161–169 (2009)

    Article  CAS  Google Scholar 

  135. V. Raikou, E. Protopapa, V. Kefala: Photo-protection from marine organisms, Rev. Clin. Pharmacol. Pharmacokinet. 25, 131–136 (2011)

    CAS  Google Scholar 

  136. A. Oren, N. Gunde-Cimerman: Mycosporines and mycosporine – like amino acids: UV protectants of multipurpose secondary metabolites?, FEMS Microbiol. Lett. 269, 1–10 (2007)

    Article  CAS  Google Scholar 

  137. R.P. Sinha, M. Klisch, A. Groniger, D.P. Hader: Mycosporine-like amino acids in the marine red alga Gracilaria cornea – Effects of UV and heat, Environ. Exp. Bot. 43, 33–43 (2000)

    Article  CAS  Google Scholar 

  138. Oyamada, M. Kaneniwa, K. Ebitani, M. Murata, K. Ishihara: Mycosporine-like amino acids extracted from scallop (Patinopecten yessoensis) ovaries: UV protection and growth stimulation activities on human cells, Biotechnol. 10, 141–150 (2008)

    CAS  Google Scholar 

  139. M. Guinea, V. Franco, L. Araujo-Bazán, I. Rodríguez-Martín, S. González: In vivo UVB-photoprotective activity of extracts from commercial marine macroalgae, Food Chem. Toxicol. 50, 1109–1117 (2012)

    Article  CAS  Google Scholar 

  140. M.J. Piao, Y.J. Hyun, S.J. Cho, H.K. Kang, E.S. Yoo, Y.S. Koh, N.H. Lee, M.H. Ko, J.W. Hyun: An ethanol extract derived from Bonnemaisonia hamifera scavenges ultraviolet B (UVB) radiation induced reactive oxygen species and attenuates UVB-induced cell damage in human keratinocytes, Mar. Drugs 10, 2826–2845 (2012)

    Article  Google Scholar 

  141. E.L. Regalado, M. Rodríguez, R. Menéndez, A.A. Concepción, C. Nogueiras, A. Laguna, A.A. Rodríguez, D.E. Williams, P. Lorenzo-Luaces, O. Valdés, Y. Hernández: Repair of UVB-damaged skin by the antioxidant sulphated flavone glycoside thalassiolin B isolated from the marine plant Thalassia testudinum Banks ex König, Mar. Biotechnol. 11, 74–80 (2009)

    Article  CAS  Google Scholar 

  142. R. Pallela, Y. Na-Young, S.K. Kim: Anti-photoaging and photoprotective compounds derived from marine organisms, Mar. Drugs 8, 1189–1202 (2010)

    Article  CAS  Google Scholar 

  143. S. Hur, H. Lee, Y. Kim, B.H. Lee, J. Shin, T.Y. Kim: Sargaquinoic acid and sargachromenol, extracts of Sargassum sagamianum, induce apoptosis in HaCaT cells and mice skin: Its potentiation of UVB-induced apoptosis, Eur. J. Pharmacol. 582, 1–11 (2008)

    Article  CAS  Google Scholar 

  144. S.J. Heo, Y.J. Jeon: Protective effect of fucoxanthin isolated from S. siliquastrum on UV-B induced cell damage, J. Photochem. Photobiol. B 95, 101–107 (2009)

    Article  CAS  Google Scholar 

  145. T. Le Costaouëc, S. Cérantola, D. Ropartz, J. Ratiskol, C. Sinquin, S. Colliec-Jouault, C. Boisset: Structural data on a bacterial exopolysaccharide produced by a deep-sea Alteromonas macleodii strain, Carbohydr. Polym. 90, 49–59 (2012)

    Article  CAS  Google Scholar 

  146. P.K. Mukherjee, N. Maity, N.K. Nema, B.K. Sarkar: Bioactive compounds from natural resources against skin aging, Phytomedicine 19, 64–73 (2011)

    Article  CAS  Google Scholar 

  147. Y. De Roeck-Holtzhauer: Intérêt Des Algues en Cosmétology et en Traitement Bucco-dentaire (Colloq. Assoc. Bucco-Dentaire, Biarritz 1984)

    Google Scholar 

  148. B. Ryu, Z.J. Qian, M.M. Kim, K.W. Nam, S.K. Kim: Anti-photoaging activity and inhibition of matrixmetalloproteinase (MMP) by marine red alga, Corallina pilulifera methanol extract, Radiat. Phys. Chem. 78, 98–105 (2009)

    Article  CAS  Google Scholar 

  149. M.J. Joe, S.N. Kim, H.Y. Choi, W.S. Shin, G.M. Park, D.W. Kang, Y.K. Kim: The inhibitory effects of eckol and dieckol from Ecklonia stolonifera on the expression of matrix metalloproteinase-1 in human dermal fibroblasts, Biol. Pharm. Bull. 29, 1735–1739 (2006)

    Article  CAS  Google Scholar 

  150. S.M. Kang, S.J. Heo, K.N. Kim, S.H. Lee, H.M. Yang, A.D. Kim, Y.J. Jeon: Molecular docking studies of a phlorotannin, dicekol isolated from Ecklonia cava with tyrosinase inhibitory activity, Bioorg. Med. Chem. 20, 311–316 (2012)

    Article  CAS  Google Scholar 

  151. T.S. Chang: An updated review of tyrosinase inhibitors, Int. J. Mol. Sci. 10, 2440–2475 (2009)

    Article  CAS  Google Scholar 

  152. T.S. Chang: Natural melanogenesis inhibitors acting through the down-regulation of tyrosinase activity, Materials 5, 1661–1685 (2012)

    Article  CAS  Google Scholar 

  153. S.H. Cha, S.C. Ko, D. Kim, Y.J. Jeon: Screening of marine algae for potential tyrosinase inhibitor: Those inhibitors reduced tyrosinase activity and melanin synthesis in zebrafish, J. Dermatol. 38(4), 343–352 (2011)

    Article  CAS  Google Scholar 

  154. X. Li, Y. Li, J.H. Jeong, K.T. Lee, H.D. Choi, B.W. Son: Screening of tyrosinase inhibiting activity from the marine-derived fungus, Korean J. Pharmacogn. 34, 138–141 (2003)

    CAS  Google Scholar 

  155. Y.X. Li, I. Wijesekara, Y. Li, S.K. Kim: Phlorotanins as bioactive agents from brown algae, Process Biochem. 46, 2219–2224 (2011)

    Article  CAS  Google Scholar 

  156. H.Y. Kang, T.J. Yoon, G.J. Lee: Whitening effects of marine pseudomonas extract, Ann. Dermatol. 23, 144–149 (2011)

    Article  CAS  Google Scholar 

  157. N.Y. Yoon, T.K. Eom, S.K. Kim: Inhibitory effect of phlorotannins isolated from Ecklonia cava on mushroom tyrosinase activity and melanin formation in mouse B16F10 melanoma cells, J. Agric. Food Chem. 57, 4124–4129 (2009)

    Article  CAS  Google Scholar 

  158. H.S. Kang, H.R. Kim, D.S. Byun, B.W. Son, T.J. Nam, J.S. Choi: Tyrosinase inhibitors isolated from the edible brown alga Ecklonia stolonifera, Arch. Pharm. Res. 27, 1226–1232 (2004)

    Article  CAS  Google Scholar 

  159. H. Shimoda, J. Tanaka, S.J. Shan, T. Maoka: Anti-pigmentary activity of fucoxanthin and its influence on skin mRNA expression of melanogenic molecules, J. Pharm. Pharmacol. 62, 1137–1145 (2010)

    Article  CAS  Google Scholar 

  160. F.W.K. Cheung, J. Guo, Y.H. Ling, C.T. Che, W.K. Liu: Anti-melanogenic property of geoditin A in murine B16 melanoma cells, Mar. Drugs 10, 465–476 (2012)

    Article  CAS  Google Scholar 

  161. J.F. Thompson, R.A. Scolyer, R.F. Kefford: Cutaneous melanoma, Lancet 365, 687–701 (2005)

    Article  CAS  Google Scholar 

  162. S.Q. Wang, R. Setlow, M. Berwick, D. Polsky, A.A. Marghoob, A.W. Kopf, R.S. Bart: Ultraviolet A and melanoma – A review, J. Am. Acad. Dermatol. 44, 837–846 (2001)

    Article  CAS  Google Scholar 

  163. K.N. Kim, G. Ahn, S.J. Heo, S.M. Kang, M.C. Kang, H.M. Yang, D. Kim, S.W. Roh, S.K. Kim, B.T. Jeon, P.J. Park, W.K. Jung, Y.J. Jeon: Inhibition of tumor growth in vitro and in vivo by fucoxanthin against melanoma B16F10 cells, Environ. Toxicol. Pharmacol. 35, 39–46 (2013)

    Article  CAS  Google Scholar 

  164. K. Tsuge, Y. Watanabe, N. Maeda, S.I. Abe, T. Tsuruhashi, T. Yoshimura, M. Yoshiki, H. Tachibana, K. Yamada: Effect of low-molecular-weight fraction of Susabi-nori water-soluble extract on HL-60 cell proliferation, J. Jpn. Soc. Food Sci. Technol. 54, 241–246 (2007)

    Article  CAS  Google Scholar 

  165. P.F. Dias, J.M. Siqueira Jr., L.F. Vendruscolo, T.D.J. Neiva, A.R. Gagliardi, M. Maraschin, R.M. Ribeiro-do-Valle: Antiangiogenic and antitumoral properties of a polysaccharide isolated from the seaweed Sargassum stenophyllum, Cancer Chemothic. Pharmacol. 56, 436–446 (2005)

    Article  CAS  Google Scholar 

  166. M.T. Ale, H. Maruyama, H. Tamauchi, J.D. Mikkelsen, A.S. Meyer: Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo, Int. J. Biol. Macromol. 49, 331–336 (2011)

    Article  CAS  Google Scholar 

  167. S. Ermakova, R. Sokolova, S.M. Kim, B.H. Um, V. Isakov, T. Zvyagintseva: Fucoidans from brown seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural characteristics and anticancer activity, Appl. Biochem. Biotechnol. 164, 841–850 (2011)

    Article  CAS  Google Scholar 

  168. J. Gao, M.T. Hamann, A. Burgos-Hernández, J.M. Ezquerra-Brauer: Bioactive peptides and depsipeptides with anticancer potential: Sources from marine animals, Mar. Drugs 10, 963–986 (2012)

    Article  CAS  Google Scholar 

  169. Y. Salma, E. Lafont, N. Therville, S. Carpentier, M.J. Bonnafé, T. Levade, Y. Génisson, N. Andrieu-Abadie: The natural anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism, Biochem. Pharmacology 78, 477–485 (2009)

    Article  CAS  Google Scholar 

  170. H.J. Choi, S.J. Bae, N.D. Kim, J.H. Jung, Y.H. Choi: Induction of apoptosis by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., in human skin melanoma cells, Int. J. Mol. Med. 14, 1091–1096 (2004)

    CAS  Google Scholar 

  171. H.C. Kwon, C.A. Kauffman, P.R. Jensen, W. Fenical: Marinomycins A–D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus `Marinispora', J. Am. Chem. Soc. 128, 1622–1632 (2006)

    Article  CAS  Google Scholar 

  172. T. Abe, A. Kukita, K. Akiyama, T. Naito, D. Uemura: Isolation and structure of a novel biindole pigment substituted with an ethyl group from a metagenomic library derived from the marine sponge Halichondria okadai, Chem. Lett. 41, 728–729 (2012)

    Article  CAS  Google Scholar 

  173. T. Vasskog, J.H. Andersen, E. Hansen, J. Svenson: Characterization and cytotoxicity studies of the rare $21:4$ n-7 acid and other polyunsaturated fatty acids from the marine opisthobranch Scaphander lignarius, isolated using bioassay guided fractionation, Mar. Drugs 10, 2676–2690 (2012)

    Article  CAS  Google Scholar 

  174. A. Campos, C.B. Souza, C. Lhullier, M. Falkenberg, E.P. Schenkel, R.M. Ribeiro-Do-Valle, J.M. Siqueira: Anti-tumour effects of elatol, a marine derivative compound obtained from red algae Laurencia microcladia, J. Pharm. Pharmacol. 64, 1146–1154 (2012)

    Article  CAS  Google Scholar 

  175. P.T. Szymanski, B. Kuppast, S.A. Ahmed, S. Khalifa, H. Fahmy: Sarcophine-diol, a skin cancer chemopreventive agent, inhibits proliferation and stimulates apoptosis in mouse melanoma B 16F 10 cell line, Mar. Drugs 10, 1–19 (2012)

    Article  CAS  Google Scholar 

  176. N. Novak, T. Bieber: Allergic and nonallergic forms of atopic diseases, J. Allergy Clin. Immunol. 112, 252–262 (2003)

    Article  Google Scholar 

  177. T.S. Vo, D.H. Ngo, S.K. Kim: Marine algae as a potential pharmaceutical source for anti-allergic therapeutics, Process Biochem. 47, 386–394 (2012)

    Article  CAS  Google Scholar 

  178. M.J. Abad, L.M. Bedoya, P. Bermejo: Natural marine anti-inflammatory products, Mini-Rev. Med. Chem. 8, 740–754 (2008)

    Article  CAS  Google Scholar 

  179. Y. Sugiura, K. Matsuda, Y. Yamada, M. Nishikawa, K. Shioya, H. Katsuzaki, K. Imai, H. Amano: Anti-allergic phlorotannins from the edible brown alga: Eisenia arborea, Food Sci. Technol. Res. 13, 54–60 (2007)

    Article  CAS  Google Scholar 

  180. Y. Sugiura, K. Matsuda, T. Okamoto, M. Kakinuma, H. Amano: Anti allergic effects of the brown alga Eisenia arborea on Brown Norway rats, Fisheries Sci. 74, 180–186 (2008)

    Article  CAS  Google Scholar 

  181. Q.T. Le, Y. Li, Z.J. Qian, M.M. Kim, S.K. Kim: Inhibitory effects of polyphenols isolated from marine alga Ecklonia cava on histamine release, Process Biochem. 44, 168–176 (2009)

    Article  CAS  Google Scholar 

  182. Y. Sugiura, K. Matsuda, Y. Yamada, M. Nishikawa, K. Shioya, H. Katsuzaki, K. Imai, H. Amano: Isolation of a new anti-allergic phlorotannin, phlorofucofuroeckol-B, from an edible brown alga, Eisenia arborea, Biosci. Biotechnol. Biochem. 70, 2807–2811 (2006)

    Article  CAS  Google Scholar 

  183. Y. Li, S.H. Lee, Q.T. Le, M.M. Kim, S.K. Kim: Antiallergic effects of phlorotannins on histamine release via binding inhibition between IgE and Fc$\varepsilon$RI, J. Agric. Food Chem. 56, 12073–12080 (2008)

    Article  CAS  Google Scholar 

  184. T. Shibata, K. Fujimoto, K. Nagayama, K. Yamaguchi, T. Nakamura: Inhibitory activity of brown algal phlorotannins against hyaluronidase, Int. J. Food Sci. Technol. 37, 703–709 (2002)

    Article  CAS  Google Scholar 

  185. Y.F. Shang, S.M. Kim, W.J. Lee, B.H. Um: Pressurized liquid method for fucoxanthin extraction from Eisenia bicyclis (Kjellman) Setchell, J. Biosci. Bioeng. 111, 237–241 (2011)

    Article  CAS  Google Scholar 

  186. I. Wijesekara, R. Pangestuti, S.K. Kim: Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae, Carbohydr. Polym. 84, 14–21 (2011)

    Article  CAS  Google Scholar 

  187. M. Asada, M. Sugie, M. Inoue, K. Nakagomi, S. Hongo, K. Murata, S. Irie, T. Takeuchi, N. Tomizuka, S. Oka: Inhibitory effect of alginic acids on hyaluronidase and on histamine release from mast cells, Biosci. Biotechnol. Biochem. 61, 1030–1032 (1997)

    Article  CAS  Google Scholar 

  188. T. Yoshida, A. Hirano, H. Wada, K. Takahashi, M. Hattori: Alginic acid oligosaccharide suppresses Th2 development and IgE production by inducing IL-12 production, Int. Arch. Allergy Immunol. 133, 239–247 (2004)

    Article  CAS  Google Scholar 

  189. K. Iwamoto, T. Hiragun, S. Takahagi, Y. Yanase, S. Morioke, S. Mihara, Y. Kameyoshi, M. Hide: Fucoidan suppresses IgE production in peripheral blood mononuclear cells from patients with atopic dermatitis, Arch. Dermatol. Res. 303, 425–431 (2011)

    Article  CAS  Google Scholar 

  190. K. Ishihara, C. Oyamada, R. Matsushima, M. Murata, T. Muraoka: Inhibitory effect of porphyran, prepared from dried Nori, on contact hypersensitivity in mice, Biosci. Biotechnol. Biochem. 69, 1824–1830 (2005)

    Article  CAS  Google Scholar 

  191. N.R. Ngatu, M.K. Okajima, M. Yokogawa, R. Hirota, M. Eitoku, B.A. Muzembo, N. Dumavibhat, M. Takaishi, S. Sano, T. Kaneko, T. Tanaka, H. Nakamura, N. Suganuma: Anti-inflammatory effects of sacran, a novel polysaccharide from Aphanothece sacrum, on 2,4,6-trinitrochlorobenzene-induced allergic dermatitis in vivo, Ann. Allergy Asthma Immunol. 108, 117–122 (2012)

    Article  CAS  Google Scholar 

  192. V.A. Ziboh, C.C. Miller, Y. Cho: Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites, Am. J. Clin. Nutr. 71, 361S–366S (2000)

    CAS  Google Scholar 

  193. M.M. McCusker, J.M. Grant-Kels: Healing fats of the skin: The structural and immunologic roles of the omega-6 and omega-3 fatty acids, Clin. Dermatol. 28, 440–451 (2010)

    Article  Google Scholar 

  194. V. Ferraro, I.B. Cruz, R.F. Jorge, F.X. Malcata, M.E. Pintado, P.M.L. Castro: Valorisation of natural extracts from marine source focused on marine by-products: A review, Food Res. Int. 43, 2221–2233 (2010)

    Article  Google Scholar 

  195. S.J. Ju, H.R. Harvey: Lipids as markers of nutritional condition and diet in the Antarctic krill Euphasia superba and Euphasia crystallorophyaduring austral winter, Deep-Sea Res. II 50, 2199–2214 (2004)

    Article  CAS  Google Scholar 

  196. L. Mondello, P.Q. Tranchida, P. Dugo, G. Dugo: Rapid, micro-scale preparation and very fast gas chromatographic separation of cod liver oil fatty acidmethyl esters, J. Pharma. Biomed. 41, 1566–1570 (2006)

    Article  CAS  Google Scholar 

  197. M. Linder, N. Belhaj, P. Sautot, E.A. Tehrany: From krill to whale: An overview of marine fatty acids and lipid compositions, OCL – Oleagineux Corps. Gras. Lipides 17, 194–204 (2010)

    Article  Google Scholar 

  198. H. Saito, S. Ishikawa: Characteristic of lipids and fatty acid compositions of the neon flying squid, Ommastrephes bartramii, J. Oleo Sci. 61, 547–564 (2012)

    Article  CAS  Google Scholar 

  199. A.P. Simopoulos: Omega-3 fatty acids in inflammation and autoimmune diseases, J. Am Coll. Nutr. 21, 495–505 (2002)

    Article  CAS  Google Scholar 

  200. A. Nicolaou, S.M. Pilkington, L.E. Rhodes: Ultraviolet-radiation induced skin inflammation: Dissecting the role of bioactive lipids, Chem. Phys. Lipids 164, 535–543 (2011)

    Article  CAS  Google Scholar 

  201. N. Moussaoui, M. Cansell, A. Denizot: Marinosomes, marine lipid-based liposomes: Physical characterization and potential application in cosmetics, Int. J. Pharm. 242, 361–365 (2002)

    Article  CAS  Google Scholar 

  202. R.P. Rastogi, Richa, R.P. Sinha, S.P. Singh, D.P. Häder: Photoprotective compounds from marine organisms, J. Ind. Microbiol. Biotechnol. 37, 537–558 (2010)

    Article  CAS  Google Scholar 

  203. N.N. Rosic, S. Dove: Mycosporine-like amino acids from coral dinoflagellates, Appl. Environ. Microbiol. 77, 248478–248486 (2011)

    Article  CAS  Google Scholar 

  204. K.H.M. Cardozo, L.G. Marques, V.M. Carvalho, M.O. Carignan, E. Pinto, P. Colepicolo: Analyses of photoprotective compounds in red algae from the Brazilian coast, Braz. J. Pharmacogn. 21, 202–208 (2011)

    Article  CAS  Google Scholar 

  205. Y.X. Xing, P. Li, Y.X. Miao, W. Du, C.B. Wang: Involvement of ROS/ASMase/JNK signalling pathway in inhibiting UVA-induced apoptosis of HaCaT cells by polypeptide from Chlamys farreri, Free Radic. Res. 42, 12–19 (2008)

    Article  CAS  Google Scholar 

  206. N.V. Thomas, S.K. Kim: Beneficial effects of marine algal compounds in cosmeceuticals, Mar. Drugs 11, 146–164 (2013)

    Article  CAS  Google Scholar 

  207. D.M.P. Shridhar, G.B. Mahajan, V.P. Kamat, C.G. Naik, R.R. Parab, N.R. Thakur, P.D. Mishra: Antibacterial activity of 2-(2',4'- dibromophenoxy)-4,6-dibromophenol from Dysidea granulose, Mar. Drugs 7, 464–471 (2009)

    Article  CAS  Google Scholar 

  208. H.P. Nguyen, D. Zhang, V. Lee, J.S. Kang, H.D. Choi, B.W. Son: Dehydrochlorofusarielin B, an antibacterial polyoxigenated decalin derivative from the marine-derived fungus Aspergillus sp, J. Nat. Prod. 70, 1188–1190 (2007)

    Article  CAS  Google Scholar 

  209. Y. Kamei, M. Sueyoshi, K. Hayashi, R. Terada, H. Nozaki: The novel anti-Propionibacterium acnes compound, sargafuran, found in the marine brown alga Sargassum macrocarpum, J. Antibiotics 62, 259–263 (2009)

    Article  CAS  Google Scholar 

  210. M. Hasui, M. Matsuda, K. Okutani, S. Shigeta: In vitro antiviral activities of sulfated polysaccharides from a marine microalga (Cochlodinium polykrikoides) against human immunodeficiency virus and other enveloped viruses, Int. J. Biol. Macromol. 17, 293–297 (1995)

    Article  CAS  Google Scholar 

  211. W. Zhu, L.C.M. Chiu, V.E.C. Ooi, P.K.S. Chan, P.O. Ang Jr.: Antiviral property and mechanism of sulphated polysaccharide from the brown alga Sargassum patents against Herpes simplex virus type 1, Phytomedcine 13, 695–701 (2006)

    Article  CAS  Google Scholar 

  212. C.A. Pujol, J.M. Estevez, M.J. Carlucci, M. Ciancia, A.S. Cerezo, E.B. Damonte: Novel DL-galactan hybrids from the red seaweed Gymnogongrus torulosus are potent inhibitors of herpes simplex virus and dengue virus, Antivir. Chem. Chemother. 13, 83–89 (2002)

    Article  CAS  Google Scholar 

  213. N.M. Ponce, C.A. Pujol, E.B. Damonte, M.L. Flores, C.A. Stortz: Fucoidans from the brown seaweed Adenocystis utricularis: Extraction methods, antiviral activity and structural studies, Carbohydr. Res. 338, 153–165 (2003)

    Article  CAS  Google Scholar 

  214. K.D. Thompson, C. Dragar: Antiviral activity of Undaria pinnatifida against herpes simplex virus, Phytotherapy Res. 18, 551–555 (2004)

    Article  Google Scholar 

  215. D.C. Rowley, S. Kelly, C.A. Kauffman, P.R. Jensen, W. Fenical: Halovirs A-E, new antiviral agents from a marine-derived fungus of the genus Scytalidium, Bioorg. Med. Chem. 11, 4263–4274 (2003)

    Article  CAS  Google Scholar 

  216. J.B. Lee, K. Hayashi, M. Hirata, E. Kuroda, E. Suzuki, Y. Kubo, T. Hayashi: Antiviral sulfated polysaccharide from Navicula directa, a diatom collected from deep-sea water in Toyama Bay, Biol. Pharm. Bull. 29, 2135–2139 (2006)

    Article  CAS  Google Scholar 

  217. X. Peng, K. Adachi, C. Chen, H. Kasai, K. Kanoh, Y. Shizuri, N. Misawa: Applied and environmental microbiology. Discovery of a marine bacterium producing 4-hydroxybenzoate and its alkyl esters, parabens, Appl. Environ. Microbiol. 72, 5556–5561 (2006)

    Article  CAS  Google Scholar 

  218. L. Mhadhebi, K. Chaieb, A. Bouraoui: Evaluation of antimicrobial activity of organic fractions of six marine algae from Tunisian Mediterranean coasts, Int. J. Pharm. Pharm. Sci. 4, 534–537 (2012)

    Google Scholar 

  219. L. Sujatha, S.S. Al-Lihaibi, S.E.N. Ayyad, M.H. Abdel-Rhman, F.A. Badria: Laurene type sesquiterpenes from the red sea red alga Laurencia obtusa as potential antitumor antimicrobial agents, Eur. J. Med. Chem. 55, 462–466 (2012)

    Article  CAS  Google Scholar 

  220. W.M. Alarif, S.S. Al-Lihaibi, S.E.N. Ayyad, M.H. Abdel-Rhman, F.A. Badria: Laurene-type sesquiterpenes from the red sea alga Laurencia obtusa as potential antitumor-antimicrobial agents, Eur. J. Med. Chem. 55, 462–466 (2012)

    Article  CAS  Google Scholar 

  221. J.S. Choi, H.J. Bae, S.J. Kim, I.S. Choi: In vitro antibacterial and anti-inflammatory properties of seaweed extracts against acne inducing bacteria, Propionibacterium acnes, J. Environ. Biol. 32, 313–318 (2011)

    Google Scholar 

  222. R.N. dos Santos Amorim, J.A.G. Rodrigues, M.L. Holanda, A.L.G. Quinderé, R.C.M. de Paula, V.M.M. Melo, N.M.B. Benevides: Antimicrobial effect of a crude sulfated polysaccharide from the red seaweed Gracilaria ornata, Braz. Arch. Biol. Technol. 55, 171–181 (2012)

    Article  CAS  Google Scholar 

  223. G. Pierre, V. Sopena, C. Juin, A. Mastouri, M. Graber, T. Maugard: Antibacterial activity of a sulfated galactan extracted from the marine alga Chaetomorpha aerea against Staphylococcus aureus, Biotechnol. Bioprocess Eng. 16, 937–945 (2011)

    Article  CAS  Google Scholar 

  224. S. Yadav, R.P. Sinha, M.B. Tyagi: Antimicrobial activity of some cyanobacteria, Int. J. Pharm. Pharm. Sci. 4, 631–635 (2012)

    Google Scholar 

  225. S. Bordbar, F. Anwar, N. Saari: High-value components and bioactives from sea cucumbers for functional foods – A review, Mar. Drugs 9, 1761–1805 (2011)

    Article  CAS  Google Scholar 

  226. T.S. Vo, D.H. Ngo, Q.V. Ta, S.K. Kim: Marine organisms as a therapeutic source against herpes simplex virus infection, Eur. J. Pharm. Sci. 44, 11–20 (2011)

    Article  CAS  Google Scholar 

  227. Hristakieva: Thalassotherapy as an alternative treatment in dermatology, Bulgarine Med. 11, 28–30 (2003)

    Google Scholar 

  228. N. Riyaz, F.R. Arakkal: Spa therapy in dermatology, Indian J. Dermatol. Venereol. Leprol. 77, 128–134 (2011)

    Article  Google Scholar 

  229. L.M. Casás, J.L. Legido, M. Pozo, L. Mourelle, F. Plantier, D. Bessières: Specific heat of mixtures of bentonitic clay with sea water or distilled water for their use in thermotherapy, Thermochim. Acta 524, 68–73 (2011)

    Article  CAS  Google Scholar 

  230. M. Suárez, P. González, R. Domínguez, A. Bravo, C. Melian, M. Pérez, I. Herrera, D. Blanco, R. Hernández, J.R. Fagund: Identification of organic compounds in San Diego de los Baños Peloid (Pinar del Rio, Cuba), J. Altern. Complementry Med. 17, 155–165 (2011)

    Article  Google Scholar 

  231. T. Pichler, J. Veizer, G.E.M. Hall: The chemical composition of shallow-water hydrothermal fluids in Tutum Bay, Ambitle Island, Papua New Guinea and their effect on ambient seawater, Marine Chem. 64, 229–252 (1999)

    Article  CAS  Google Scholar 

  232. El-Hinnawi, S.D. Abayazeed: The suitability of some Egyptian smectitic clays for mud therapy, J. Appl. Sci. 12, 480–485 (2012)

    Article  CAS  Google Scholar 

  233. N. Gros, M.F. Camões, C. Oliveira, M.C.R. Silva: Ionic composition of seawaters and derived saline solutions determined by ion chromatography and its relation to other water quality parameters, J. Chromatogr. A 1210, 92–98 (2008)

    Article  CAS  Google Scholar 

  234. K. Murugaiyan, K. Sivakumar: Seasonal variation in elemental composition of Stoechospermum marginatum (Ag.) Kutz and Sargassum wightii (Greville Mscr.) J. G. Agardh in relation to chemical composition of seawater, Colloids Surf, B: Biointerfaces 64, 140–144 (2008)

    CAS  Google Scholar 

  235. W.T. Liao, T.S. Huang, C.C. Chiu, J.L. Pan, S.S. Liang, B.H. Chen, S.H. Chen, P.L. Liu, H.C. Wang, Z.H. Wen, H.M. Wang, S.W. Hsiao: Biological properties of acidic cosmetic water from seawater, Int. J. Mol. Sci. 13, 5952–5971 (2012)

    Article  CAS  Google Scholar 

  236. T.G. Polefka, R.J. Bianchini, S. Shapiro: Interaction of mineral salts with the skin: a literature survey, Int. J. Cosmet. Sci. 34, 416–423 (2012)

    Article  CAS  Google Scholar 

  237. Proksch, H.P. Nissen, M. Bremgartner, C. Urquhart: Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin, Int. J. Dermatol. 44, 151–157 (2005)

    Article  Google Scholar 

  238. B. Abu-Jdayil, H.A. Mohameed: A facial mask comprising dead sea mud, J. Cosmet. Sci. 57, 441–454 (2006)

    Google Scholar 

  239. S.P. Nisticò, M. Gabellini, R. Saraceno, C. Schipani, S. Chimenti: A balneoterapia termale: Applicazioni dermatologiche, J. Plastic Dermatol. 5, 287–291 (2009)

    Google Scholar 

  240. M. Harari: Beauty is not only skin deep: The Dead Sea: Features and cosmetics. In: Medical Hydrology and Balneology: Environmental Aspects, Balnea, Vol. 6, ed. by F. Maraver, M.Z. Karagülle (Universidad Complutense de Madrid, Madrid 2012) p. 127

    Google Scholar 

  241. S.K. Kim, J. Venkatesan, P.N. Sudha: Sea water and sea mud: Cosmeceuticals application. In: Marine Cosmeceuticals. Trends and Prospects, ed. by S.K. Kim (CRC, Boca Raton 2011) pp. 240–255

    Chapter  Google Scholar 

  242. C. Morer, A. Cerrada, A. Michán, F. Maraver: Is thalassotherapy simply a type of climatotherapy? No, certainly, it's not. In: Medical Hydrology and Balneology: Environmental Aspects, Balnea, Vol. 6, ed. by F. Maraver, M.Z. Karagülle (Universidad Complutense de Madrid, Madrid 2012) pp. 102–103

    Google Scholar 

  243. M. de Carames Gouvea: Seaweed in cosmetics, Cosmet. Toilet. 95, 47–50 (1980)

    Google Scholar 

  244. D. Cernanov, R. Kulkarni, R. Macchio, A. Menzel, J. Hayward: Protecting the skin, Cosmet. Toilet. 112, 47–52 (1997)

    Google Scholar 

  245. X. Yan, Y. Chuda, M. Suzuki, T. Nagata: Fucoxanthin as the major antioxidant in Hijikia fusiforme, a common edible seaweed, Biosci. Biotechnol. Biochem. 63, 605–607 (1999)

    Article  CAS  Google Scholar 

  246. W. Fenical: Exploring marine derives ingredients for personal care, Cosmetics Toilet. 116, 33–37 (2001)

    CAS  Google Scholar 

  247. Maeda, M. Hosokawa, T. Sashima, K. Funayama, K. Miyashita: Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues, Biochem. Biophys. Res. Commun. 332, 392–397 (2005)

    Article  CAS  Google Scholar 

  248. T. Yokota, M. Nagashima, M. Ghazizadeh, O. Kawanami: Increased effect of fucoidan on lipoprotein lipase secretion in adipocytes, Life Sci. 84, 523–529 (2009)

    Article  CAS  Google Scholar 

  249. T. Al-Bader, A. Byrne, J. Gillbro, A. Mitarotonda, A. Metois, F. Vial, A.V. Rawlings, A. Laloeuf: Effect of cosmetic ingredients as anticellulite agents: Synergisticaction of actives with in vitro and in vivo efficacy, J. Cosmet. Dermatol. 11, 17–26 (2012)

    Article  Google Scholar 

  250. E. Berardesca, E. Abril, C. Rona, R. Vesnaver, A. Cenni, M. Oliva: An effective night slimming topical treatment, Int. J. Cosmet. Sci. 34, 263–272 (2012)

    Article  CAS  Google Scholar 

  251. J.I. Kang, S.C. Kim, M.K. Kim, H.J. Boo, Y.J. Jeon, Y.S. Koh, E.S. Yoo, S.M. Kang, H.K. Kang: Effect of dieckol, a component of Ecklonia cava, on the promotion of hair growth, Int. J. Mol. Sci. 13, 6407–6423 (2012)

    Article  CAS  Google Scholar 

  252. E. Voultsiadou: Therapeutic properties and uses of marine invertebrates in the ancient Greek world and early Byzantium, J. Ethnopharmacology 130, 237–247 (2010)

    Article  Google Scholar 

  253. J.I.I.I. Kang, S.C. Kim, S.C. Han, H.J. Hong, Y.J. Jeon, B. Kim, Y.S. Koh, E.S. Yoo, H.K. Kang: Hair-loss preventing effect of Grateloupia elliptica, Biomol. Therapy 20, 118–124 (2012)

    Article  CAS  Google Scholar 

  254. S.G. Fard, F.T. Shamsabadi, M. Emadi, G.Y. Meng, K. Muhammad, S. Mohamed: Ethanolic extract of Eucheuma cottonii promotes in vivo hair growth and wound healing, J. Anim. Vet. Adv. 10, 601–605 (2011)

    Article  Google Scholar 

  255. J.H. Fitton, M. Irhimeh: Macroalgae in nutricosmetics, Cosmetics Toilet. 123, 93–100 (2008)

    CAS  Google Scholar 

  256. S. Gaigi, J. Elati, A. Ben Osman, C. Beji: Etude experimentale de l'effet des algues marines dans le traitement de l'obesite (Seaweed, algae and obesity: A trial study), Tunis. Medicale 74, 241–243 (1996)

    CAS  Google Scholar 

  257. D. Hexsel, M. Soirefmann: Cosmeceuticals for cellulite, Semin. Cutan. Med. Surg. 30, 167–170 (2011)

    Article  CAS  Google Scholar 

  258. T. Fujimura, Y. Shibuya, S. Moriwaki, K. Tsukahara, T. Kitahara, T. Sano, Y. Nishizawa, Y. Takema: Fucoidan is the active component of Fucus vesiculosus that promotes contraction of fibroblast-populated collagen gels, Biol. Pharm. Bull. 23, 1180–1184 (2000)

    Article  CAS  Google Scholar 

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Balboa, E.M., Conde, E., Soto, M.L., Pérez-Armada, L., Domínguez, H. (2015). Cosmetics from Marine Sources. In: Kim, SK. (eds) Springer Handbook of Marine Biotechnology. Springer Handbooks. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-53971-8_44

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