β-Blockers or Clonidine in Antihypertensive Therapy?
β-receptor blockers are often considered as agents of first choice in antihypertensive therapy (Kewitz 1978). Side-effects are seldom, contraindications must be noted; in bronchial asthma, β-blockers are contraindicated (Burley 1975; Frishman 1979). We carried out a retrospective investigation of 100 randomly sampled hypertensive patients (bronchial asthma had not been noted in the history) treated with β-blockers and with clonidine. Airway resistance, chest complaints and history of respiratory diseases were compared and the incidence of bronchial side-effects by high-dose (e.g. antihypertensive) β-blocker therapy measured.
KeywordsPropranolol Dine Rhinitis Clonidine Bronchitis
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