Abstract
The view of how metabolism influences acid-base status has been changed and questioned several times during the past few years. For aerobic steady state metabolism a major stimulus arose from a paper by Atkinson and Camien (1982), which by the application of stoichiometric principles led to a reconsideration of the importance of protein/amino acid catabolism and of urea synthesis in acid-base regulation. At the same time using stoichiometric principles also led to a quantification of the influences of non-steady state (anaerobic, exercise) metabolism on the acid-base status (Pörtner et al. 1984; Pörtner 1987, 1989). All of these considerations provide a basis for a general and quantitative understanding of the relationships between metabolic and acid-base regulation.
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© 1995 Springer-Verlag Berlin Heidelberg
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Pörtner, H.O. (1995). pH Homeostasis in Terrestrial Vertebrates: A Comparison of Traditional and New Concepts. In: Heisler, N. (eds) Mechanisms of Systemic Regulation: Acid—Base Regulation, Ion-Transfer and Metabolism. Advances in Comparative and Environmental Physiology, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-52363-2_3
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DOI: https://doi.org/10.1007/978-3-642-52363-2_3
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