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Koronare Herzerkrankung und akuter Herzinfarkt — Aktuelle Aspekte der Pathogenese, Symptomatologie und des klinischen Verlaufs

  • Conference paper
Pathobiochemie, Molekularbiologie und moderne Diagnostik kardiovaskulärer Erkrankungen

Part of the book series: Zusammenarbeit von Klinik und Klinischer Chemie ((ZUSAMMENARBEIT))

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Zusammenfassung

Unter den klinischen Manifestationen der koronaren Herzerkrankung ist der akute Myokardinfarkt für Patient und Arzt gleichermaßen die dramatischste Erscheinungsform. Wie der plötzliche Herztod, die symptomatische und asymptomatische (stumme) Myokardischämie gehört er zu den ischämischen Syndromen. Die Herzinsuffizienz nach Myokardinfarkt ist dagegen ein Folgezustand nach abgelaufener transmuraler Ischämie. Rhythmusstörungen können sowohl während akuter ischämischer Ereignisse als auch nach abgelaufenem Infarkt auftreten und haben ihren Ursprung meist im arrhythmogenen Substrat, d.h. den noch nicht vernarbten, häufig noch ischämischen Randzonen von Infarkten. Wenn es sich dabei um anhaltende Kammertachykardien oder um Kammerflimmern handelt, sind sie die Ursache des plötzlichen Herztodes.

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  1. Abt. Innere Medizin-Kardiologie des Zentrums Innere Medizin, Philipps-Universität, Baldingerstr, Postfach 2360, D-35033, Marburg, Deutschland

    Bernhard Maisch, Michael Steliwaag & Bernd C. Simon

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  1. Institut für Klinische Chemie und Pathobiochemie, Rheinisch-Westfälischen Technischen Hochschule Aachen, Pauwelsstraße 30, D-52057, Aachen, Deutschland

    H. Greiling

  2. Diagnostische Forschung, E. Merck, Darmstadt, Frankfurter Straße 250, D-64271, Darmstadt, Deutschland

    Siegfried Neumann

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Maisch, B., Steliwaag, M., Simon, B.C. (1994). Koronare Herzerkrankung und akuter Herzinfarkt — Aktuelle Aspekte der Pathogenese, Symptomatologie und des klinischen Verlaufs. In: Greiling, H., Neumann, S. (eds) Pathobiochemie, Molekularbiologie und moderne Diagnostik kardiovaskulärer Erkrankungen. Zusammenarbeit von Klinik und Klinischer Chemie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-52362-5_6

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