Detection of Very Early Atherosclerosis by Duplex Sonography

  • M. Ludwig
Conference paper


In this study, aortas of 12 rabbits with experimentally induced atherosclerosis were investigated by duplex sonography. The sonographic features of the aortic vessel wall showed parallel wall contours enclosing a hypoechoic space. In vivo experiments in rabbit aortas document the distance between these contours correlating histologically with high cholesterol diet. This diet caused a broadening of the hypoechoic space in the rabbit aortic vessel wall. A comparable correlation was found between the width of the hypoechoic space and the severity of atherosclerotic changes.

The data demonstrate that duplex sonography is a useful non-invasive approach for detection of very early atherosclerotic changes in arterial vessel walls before plaques can be identified.


Duplex Sonography High Cholesterol Diet Atherosclerotic Change Early Atherosclerosis Rabbit Aorta 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • M. Ludwig
    • 1
  1. 1.Medizinische PoliklinkUniversity of BonnGermany

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