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Evaluation and Comparison of Various Strategies for Estimating Local Cerebral Glucose Metabolic Rate from Brain Images in Positron Emission Tomography

  • Chin-Tu Chen
  • Malcolm D. Cooper
  • Robert N. Beck
Conference paper

Abstract

Positron emission tomography (PET) in use with F-18 labeled deoxyglucose (FDG) has received considerable attention in recent years for its role in studies of cerebral glucose metabolism. PET measurements, combined with a mathematical model describing the biochemical and physiological processes of deoxyglucose (DG) and glucose, permit noninvasive assessments of local cerebral metabolic rate of glucose (LCMRG). This study investigates various strategies of estimating LCMRG from PET data. Their computation requirements are compared and their sensitivities to experimental errors associated with various parameters are examined.

Keywords

Positron Emission Tomography Positron Emission Tomography Image Positron Emission Tomography Scan Positron Emission Tomography Data Noninvasive Assessment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag, Berlin, Heidelberg 1985

Authors and Affiliations

  • Chin-Tu Chen
    • 1
  • Malcolm D. Cooper
    • 1
  • Robert N. Beck
    • 1
  1. 1.Department of Radiology and the Franklin McLean Memorial Research InstitueThe University of ChicagoUSA

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