The Effect of High Extracellular Potassium on the Kinetics of Potassium Conductance of the Squid Axon Membrane

  • W. Stühmer
  • F. Conti

Abstract

K currents were studied under voltage clamp in intact axons or in axons perfused intracellularly with solutions containing 300 meq-K+, sucrose and phosphate ions at pH 7.3. The axons were superfused with extracellular solutions containing: (460 − x) mM-NaCl (or TMACl); x mM-KCl; 50 mM-CaC12; .5 μM-TTX; 5 mM-TrisCl buffer; pH 7.8; 0≦x≦460.

Keywords

Sucrose 

References

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    Frankenhaeuser,B., Hodgkin,A.L. 1956 J. Physiol. 131: 341–376PubMedGoogle Scholar
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    Dubois,J.M., Bergman,C. 1977 Pflügers Arch. 370: 185–194PubMedCrossRefGoogle Scholar
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    Hille,B., Schwarz,W. 1978 J. Physiol. 72: 409–442Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • W. Stühmer
    • 1
  • F. Conti
    • 2
  1. 1.Fachbereich Physik E17Technische UniversitätMünchenGermany
  2. 2.Laboratorio di Cibernetica e Biofisica (CNR)CamogliItaly

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