The Effect of High Extracellular Potassium on the Kinetics of Potassium Conductance of the Squid Axon Membrane

  • W. Stühmer
  • F. Conti


K currents were studied under voltage clamp in intact axons or in axons perfused intracellularly with solutions containing 300 meq-K+, sucrose and phosphate ions at pH 7.3. The axons were superfused with extracellular solutions containing: (460 − x) mM-NaCl (or TMACl); x mM-KCl; 50 mM-CaC12; .5 μM-TTX; 5 mM-TrisCl buffer; pH 7.8; 0≦x≦460.


Voltage Clamp Extracellular Solution Tail Current Potassium Conductance Deutsche Gesellschaft 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • W. Stühmer
    • 1
  • F. Conti
    • 2
  1. 1.Fachbereich Physik E17Technische UniversitätMünchenGermany
  2. 2.Laboratorio di Cibernetica e Biofisica (CNR)CamogliItaly

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