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Interactions of ATP Phosphate Groups with Amines and Divalent Metal Ions: 31P-NMR Studies

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Annual Meeting of the Deutsche Gesellschaft für Biophysik
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Abstract

The mechanism of uptake, storage, and release of several biogenic amines acting as neuronal transmitters (as well as the molecular effect of some psychoactive catecholamines) seems to be determined essentially by the interaction of the amines with adenosine-5’-triphosphate (ATP). 31P-NMR spectroscopy of the ATP phosphorous groups has been used for determining the uptake of amines by chromaffin granules1) and investigating qualitatively the involvement of the different phosphate groups in the association with catecholamines2) or divalent metal ions3).

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Reference

  1. Casey,R.P.,Njus,D.,Radda,G.K.,Sehr,P.A.:Biochem.16(1977)972–977

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  2. Granot,J.: FEBS Lett. 88(1978)283–286

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  3. Cohn,M.,Hughes,T.R.: J.Biol.Chem. 237(1962)176–181

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  4. Sapper,H.,Gohl,W.,Matthies,M.,Haas-Ackermann,I.,Lohmann,W.: Cell.Mol.Biol.(submitted for publication)

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© 1979 Springer-Verlag Berlin Heidelberg

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Sapper, H., Gohl, W., Lohmann, W. (1979). Interactions of ATP Phosphate Groups with Amines and Divalent Metal Ions: 31P-NMR Studies. In: Adam, G., Stark, G. (eds) Annual Meeting of the Deutsche Gesellschaft für Biophysik. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51881-2_15

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  • DOI: https://doi.org/10.1007/978-3-642-51881-2_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-09684-9

  • Online ISBN: 978-3-642-51881-2

  • eBook Packages: Springer Book Archive

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