Modification of DNA Ploidy in Rectal Cancer Following Pre-Operative Radiotherapy

  • M. J. C. Matter
  • S. Rowley
  • G. D. Oates
Conference paper

Abstract

Recent studies on colorectal cancer [1–6] and on rectal cancer alone [7–10] using flow cytometry analysis have demonstrated the prognostic role of DNA stemline assessment. Selected patients who underwent a curative resection for a DNA aneuploid tumour had a higher local recurrence rate and a lower survival rate. DNA content of pre-operative biopsies may reflect the content of the resected primary [11] and thus afford an additional factor in pre-operative staging, as proposed by Williams et al. [12].

Keywords

Rectal Cancer Preoperative Radiotherapy Colorectal Adenocarcinoma Radiotherapy Group Preoperative Biopsy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • M. J. C. Matter
  • S. Rowley
  • G. D. Oates

There are no affiliations available

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