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Modification of DNA Ploidy in Rectal Cancer Following Pre-Operative Radiotherapy

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Abstract

Recent studies on colorectal cancer [1–6] and on rectal cancer alone [7–10] using flow cytometry analysis have demonstrated the prognostic role of DNA stemline assessment. Selected patients who underwent a curative resection for a DNA aneuploid tumour had a higher local recurrence rate and a lower survival rate. DNA content of pre-operative biopsies may reflect the content of the resected primary [11] and thus afford an additional factor in pre-operative staging, as proposed by Williams et al. [12].

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© 1992 Springer-Verlag Berlin Heidelberg

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Matter, M.J.C., Rowley, S., Oates, G.D. (1992). Modification of DNA Ploidy in Rectal Cancer Following Pre-Operative Radiotherapy. In: Givel, JC., Oates, G.D., Thomson, J.P.S. (eds) Updates in Colo-Proctology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51680-1_16

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  • DOI: https://doi.org/10.1007/978-3-642-51680-1_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-55327-4

  • Online ISBN: 978-3-642-51680-1

  • eBook Packages: Springer Book Archive

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