Modification of DNA Ploidy in Rectal Cancer Following Pre-Operative Radiotherapy

  • M. J. C. Matter
  • S. Rowley
  • G. D. Oates
Conference paper


Recent studies on colorectal cancer [1–6] and on rectal cancer alone [7–10] using flow cytometry analysis have demonstrated the prognostic role of DNA stemline assessment. Selected patients who underwent a curative resection for a DNA aneuploid tumour had a higher local recurrence rate and a lower survival rate. DNA content of pre-operative biopsies may reflect the content of the resected primary [11] and thus afford an additional factor in pre-operative staging, as proposed by Williams et al. [12].


Rectal Cancer Preoperative Radiotherapy Colorectal Adenocarcinoma Radiotherapy Group Preoperative Biopsy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • M. J. C. Matter
  • S. Rowley
  • G. D. Oates

There are no affiliations available

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