The use of Contour Plots for Interpretation of Multi-Drug Combination

  • M. J. de Matos Barbosa
Conference paper
Part of the Lecture Notes in Medical Informatics book series (LNMED, volume 40)


A combination of more than two drugs makes it difficult to find the optimal treatment level. One way to analyse such combinations is through Regression analysis. To help in the analysis various kinds of contour plots can be generated from the Regression model used. They can be very helpful in the interpretation of the multi-relations-ships occured by the drug combinations. Where the number of interactions grows exponentially with the number of drugs used in the treatment. However, by considering combinations of constant response, the dimensions can be decreased by one, marking it easier to interpret the relationships existing between all drugs in the combination.


Response Surface Contour Plot Hazard Function Drug Combination Relative Hazard 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • M. J. de Matos Barbosa
    • 1
  1. 1.Faculty of MedicineUniversity of CoimbraPortugal

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